Publications
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Treatment of chronic airway diseases using nutraceuticals: Mechanistic insight.
(2022). Critical reviews in food science and nutrition, . vol. 62, ss. 7576-7590 DOI -
Neutrophil extracellular traps promote cancer-associated inflammation and myocardial stress..
(2022). Oncoimmunology, . vol. 11 DOI -
The ingenious mast cell: Contemporary insights into mast cell behavior and function.
(2022). Allergy. European Journal of Allergy and Clinical Immunology, . vol. 77, ss. 83-99 DOI -
Serglycin Is Involved in Adipose Tissue Inflammation in Obesity.
(2022). Journal of Immunology, . vol. 208, ss. 121-132 DOI -
Differential expression of enzymes in thymidylate biosynthesis in zebrafish at different developmental stages: implications for dtymk mutation-caused neurodegenerative disorders.
(2022). BMC neuroscience (Online), . vol. 23 DOI -
Structural and functional analysis of human thymidylate kinase isoforms.
(2022). Nucleosides, Nucleotides & Nucleic Acids, . vol. 41, ss. 321-332 DOI -
Heavy metal tolerance of Mesorhizobium delmotii thymidylate kinase.
(2022). Nucleosides, Nucleotides & Nucleic Acids, . vol. 41, ss. 1305-1317 DOI -
Mefloquine causes selective mast cell apoptosis in cutaneous mastocytosis lesions by a secretory granule-mediated pathway.
(2022). Experimental dermatology, . vol. 31, ss. 1729-1740 DOI -
Mast cell chymase has a negative impact on human osteoblasts.
(2022). Matrix Biology, . vol. 112, ss. 1-19 DOI -
Monensin inhibits mast cell mediated airway contractions in human and guinea pig asthma models.
(2022). Scientific Reports, . vol. 12 DOI -
Quantitative In-Depth Transcriptome Analysis Implicates Peritoneal Macrophages as Important Players in the Complement and Coagulation Systems.
(2022). International Journal of Molecular Sciences, . vol. 23 DOI -
Tryptase reference values in a Swedish middle-aged general population and association with diabetes mellitus.
(2022). Clinical and Experimental Allergy, . ss. 1-4 DOI -
Mast cell chymase affects the functional properties of primary human airway fibroblasts: Implications for asthma..
(2022). Journal of Allergy and Clinical Immunology, . vol. 149, ss. 718-727 DOI -
Mast cell chymase regulates extracellular matrix remodeling-related events in primary human small airway epithelial cells.
(2022). Journal of Allergy and Clinical Immunology, . vol. 150, ss. 1534-1544 DOI -
Tryptase Regulates the Epigenetic Modification of Core Histones in Mast Cell Leukemia Cells.
(2021). Frontiers in Immunology, vol. 12 DOI -
Glutamate triggers the expression of functional ionotropic and metabotropic glutamate receptors in mast cells.
(2021). Cellular & Molecular Immunology, . vol. 18, ss. 2383-2392 DOI -
Platelet α-granule cargo packaging and release are affected by the luminal proteoglycan, serglycin.
(2021). Journal of Thrombosis and Haemostasis, vol. 19, ss. 1082-1095 DOI -
Biochemical Characterizations of Human TMPK Mutations Identified in Patients with Severe Microcephaly: Single Amino Acid Substitutions Impair Dimerization and Abolish Their Catalytic Activity.
(2021). ACS Omega, . vol. 6, ss. 33943-33952 DOI -
Monensin induces selective mast cell apoptosis through a secretory granule-mediated pathway..
(2021). Allergy. European Journal of Allergy and Clinical Immunology . DOI -
Novel Strategies to Target Mast Cells in Disease.
(2021). Journal of Innate Immunity, . vol. 13, ss. 131-147 DOI -
Mast cell tryptase potentiates neutrophil extracellular trap formation.
(2021). Journal of Innate Immunity, ss. 1-14 DOI -
Mast Cell Degranulation Increases Mouse Mast Cell Protease 4-Dependent Vasopressor Responses to Big Endothelin-1 But Not Angiotensin I.
(2021). Journal of Pharmacology and Experimental Therapeutics, vol. 376, ss. 213-221 DOI -
Dynamin inhibition causes context-dependent cell death of leukemia and lymphoma cells.
(2021). PLOS ONE, . vol. 16 DOI -
Quantitative In-Depth Analysis of the Mouse Mast Cell Transcriptome Reveals Organ-Specific Mast Cell Heterogeneity.
(2020). CELLS, . vol. 9 DOI -
How Relevant Are Bone Marrow-Derived Mast Cells (BMMCs) as Models for Tissue Mast Cells?: A Comparative Transcriptome Analysis of BMMCs and Peritoneal Mast Cells.
(2020). Cells, . vol. 9 DOI -
Mast Cell β-Tryptase Is Enzymatically Stabilized by DNA.
(2020). International Journal of Molecular Sciences, vol. 21 DOI -
Histone Methyltransferase Inhibition Has a Cytotoxic Impact on Transformed Mast Cells: Implications for Mastocytosis.
(2020). Anticancer Research, . vol. 40, ss. 2525-2536 DOI -
Do Mast Cells Have a Role in Tendon Healing and Inflammation?.
(2020). Cells, vol. 9 DOI -
Identification of a novel thymidylate kinase activity..
(2020). Nucleosides, Nucleotides & Nucleic Acids, vol. 39, ss. 1359-1368 DOI -
Protective role of mouse mast cell tryptase Mcpt6 in melanoma..
(2020). Pigment Cell & Melanoma Research, vol. 33, ss. 579-590 DOI -
Novel aspects of mast cell and basophil function: Highlights from the 9th meeting of the European Mast Cell and Basophil Research Network (EMBRN)-A Marcus Wallenberg Symposium.
(2020). Allergy. European Journal of Allergy and Clinical Immunology, . vol. 75, ss. 707-708 DOI -
Mast cell chymase protects against acute ischemic kidney injury by limiting neutrophil hyperactivation and recruitment.
(2020). Kidney International, . vol. 97, ss. 516-527 DOI -
Mouse connective tissue mast cell proteases tryptase and carboxypeptidase A3 play protective roles in itch induced by endothelin-1.
(2020). Journal of Neuroinflammation, . vol. 17 DOI -
Urticaria: Collegium Internationale Allergologicum (CIA) Update 2020.
(2020). International Archives of Allergy and Immunology, vol. 181, ss. 321-333 DOI -
DNA demethylation regulates gene expression in IgE-activated mouse mast cells..
(2020). Allergy. European Journal of Allergy and Clinical Immunology, vol. 75, ss. 1776-1780 DOI -
Novel Insight into the in vivo Function of Mast Cell Chymase: Lessons from Knockouts and Inhibitors.
(2020). Journal of Innate Immunity, . vol. 12, ss. 357-372 DOI -
Experimental Autoimmune Encephalomyelitis Potentiates Mouse Mast Cell Protease 4-Dependent Pressor Responses to Centrally or Systemically Administered Big Endothelin-1.
(2019). Journal of Pharmacology and Experimental Therapeutics, vol. 370, ss. 437-446 DOI -
Local delivery of temozolomide via a biologically inert carrier (Temodex) prolongs survival in glioma patients, irrespectively of the methylation status of MGMT.
(2019). Neoplasma (Bratislava), . vol. 66, ss. 288-293 DOI -
The Absence of Tryptase Mcpt6 Causes Elevated Cellular Stress in Response to Modulation of the Histone Acetylation Status in Mast Cells.
(2019). Cells, vol. 8 DOI -
Exosome-mediated uptake of mast cell tryptase into the nucleus of melanoma cells: a novel axis for regulating tumor cell proliferation and gene expression.
(2019). Cell Death and Disease, . vol. 10 DOI -
Lysosomotropic challenge of mast cells causes intra-granular reactive oxygen species production.
(2019). Cell Death Discovery, vol. 5 DOI -
The emerging role of mast cell proteases in asthma.
(2019). European Respiratory Journal, vol. 54 -
The emerging role of mast cell proteases in asthma.
(2019). European Respiratory Journal, . vol. 54 DOI -
Mouse Mast Cell Protease-4 Recruits Leukocytes in the Inflammatory Phase of Surgically Wounded Skin.
(2019). ADVANCES IN WOUND CARE, . vol. 8 8, ss. 469 469-475 475 DOI -
Mouse mast cell protease 4 suppresses scar formation after traumatic spinal cord injury.
(2019). Scientific Reports, . vol. 9 DOI -
Streptococcal sagA activates a proinflammatory response in mast cells by a sublytic mechanism.
(2019). Cellular Microbiology, . vol. 21 DOI -
The controversial role of mast cells in fibrosis.
(2018). Immunological Reviews, . vol. 282, ss. 198-231 DOI -
Mitogen-Activated Protein Kinase Signaling Regulates Proteoglycan Composition of Mast Cell Secretory Granules.
(2018). Frontiers in Immunology, . vol. 9 DOI -
Mast cell chymase decreases the severity of group B Streptococcus infections.
(2018). Journal of Allergy and Clinical Immunology, vol. 142, ss. 120-129 DOI -
Mouse Mast Cell Protease 4 Deletion Protects Heart Function and Survival After Permanent Myocardial Infarction.
(2018). Frontiers in Pharmacology, vol. 9 DOI -
The Effect of Lipopolysaccharide-Induced Experimental Bovine Mastitis on Clinical Parameters, Inflammatory Markers, and the Metabolome: A Kinetic Approach.
(2018). Frontiers in Immunology, . vol. 9 DOI -
Mouse mast cells and mast cell proteases do not play a significant role in acute tissue injury pain induced by formalin.
(2018). Molecular Pain, vol. 14 DOI -
Mast Cell Degranulation Exacerbates Skin Rejection by Enhancing Neutrophil Recruitment.
(2018). Frontiers in Immunology, vol. 9 DOI -
Increased mast cell degranulation and co-localization of mast cells with the NMDA receptor-1 during healing after Achilles tendon rupture.
(2017). Cell and Tissue Research, . vol. 370, ss. 451-460 DOI -
Inhibition of the BET family of epigenetic reader proteins: A novel principle for modulating gene expression in IgE-activated mast cells.
(2017). Immunity, Inflammation and Disease, vol. 5, ss. 141-150 DOI -
The combined action of mast cell chymase, tryptase and carboxypeptidase A3 protects against melanoma colonization of the lung.
(2017). OncoTarget, . vol. 8, ss. 25066-25079 DOI -
Siramesine causes preferential apoptosis of mast cells in skin biopsies from psoriatic lesions.
(2017). British Journal of Dermatology, vol. 177, ss. 179-187 DOI -
Copper Regulates Maturation and Expression of an MITF: Tryptase Axis in Mast Cells.
(2017). Journal of Immunology, vol. 199, ss. 4132-4141 DOI -
Excessive dietary intake of vitamin A reduces skull bone thickness in mice.
(2017). PLOS ONE, vol. 12 DOI -
Tryptase-catalyzed core histone truncation: A novel epigenetic regulatory mechanism in mast cells.
(2017). Journal of Allergy and Clinical Immunology, . vol. 140, ss. 474-485 DOI -
Induction of Human Lung Mast Cell Apoptosis by Granule Permeabilization: A Novel Approach for Targeting Mast Cells.
(2017). Frontiers in Immunology, vol. 8 DOI -
Acidic pH is essential for maintaining mast cell secretory granule homeostasis.
(2017). Cell Death and Disease, . vol. 8 DOI -
Mast cells and McPT4 chymase Promote renal impairment after Partial Ureteral Obstruction.
(2017). Frontiers in Immunology, . vol. 8 DOI -
Proteome analysis of mast cell releasates reveals a role for chymase in the regulation of coagulation factor XIIIA levels via proteolytic degradation.
(2017). Journal of Allergy and Clinical Immunology, . vol. 139, ss. 323-334 DOI -
Equine Airway Mast Cells are Sensitive to Cell Death Induced by Lysosomotropic Agents.
(2017). Scandinavian Journal of Immunology, . vol. 85, ss. 30-34 DOI -
Significant Contribution of Mouse Mast Cell Protease 4 in Early Phases of Experimental Autoimmune Encephalomyelitis.
(2016). Mediators of Inflammation DOI -
Endothelin receptor antagonist macitentan or deletion of mouse mast cell protease 4 delays lesion development in atherosclerotic mice.
(2016). Life Sciences, . vol. 159, ss. 71-75 DOI -
Mastitis Pathogens with high Virulence in a Mouse Model Produce a Distinct cytokine Profile In Vivo.
(2016). Frontiers in Immunology, vol. 7 DOI -
The Role of Mast Cells in Bacterial Infection.
(2016). American Journal of Pathology, vol. 186, ss. 4-14 DOI -
Live Staphylococcus aureus Induces Expression and Release of Vascular Endothelial Growth Factor in Terminally Differentiated Mouse Mast Cells.
(2016). Frontiers in Immunology, vol. 7 DOI -
Increased Bone Mass in Female Mice Lacking Mast Cell Chymase.
(2016). PLOS ONE, vol. 11 DOI -
Activated mast cells promote differentiation of B cells into effector cells.
(2016). Scientific Reports, vol. 6 DOI -
Serglycin determines secretory granule repertoire and regulates natural killer cell and cytotoxic T lymphocyte cytotoxicity.
(2016). The FEBS Journal, vol. 283, ss. 947-961 DOI -
IGF-1 degradation by mouse mast cell protease 4 promotes cell death and adverse cardiac remodeling days after a myocardial infarction.
(2016). Proceedings of the National Academy of Sciences of the United States of America, vol. 113, ss. 6949-6954 DOI -
Mast cells promote scar remodeling and functional recovery after spinal cord injury via mouse mast cell protease 6.
(2016). The FASEB Journal, vol. 30, ss. 2040-2057 DOI -
IL-6 and IL-17A degradation by mast cells is mediated by a serglycin: serine protease axis.
(2016). Immunity, Inflammation and Disease, vol. 4, ss. 70-79 DOI -
Mast cells promote melanoma colonization of lungs.
(2016). OncoTarget, vol. 7, ss. 68990-69001 DOI -
Approaches for analyzing the roles of mast cells and their proteases in vivo.
(2015). Advances in Immunology, vol. 126, ss. 45-127 DOI -
Damnacanthal inhibits IgE receptor-mediated activation of mast cells.
(2015). Molecular Immunology, vol. 65, ss. 86-93 DOI -
Ablation of human skin mast cells in situ by lysosomotropic agents.
(2015). Experimental dermatology, vol. 24, ss. 516-521 DOI -
Serglycin protects against high fat diet-induced increase in serum LDL in mice.
(2015). Glycoconjugate Journal, vol. 32, ss. 703-714 DOI -
Induction of mast cell apoptosis by a novel secretory granule-mediated pathway..
(2015). Methods in Molecular Biology, vol. 1220, ss. 325-37 DOI -
MAST CELL GRANULES: ARMED WITH HISTAMINE AND FRIENDS.
(2015). Inflammation Research, vol. 64, ss. S8-S8 -
Serglycin protects against high fat diet-induced increase in plasma LDL in mice.
(2015). Glycoconjugate Journal -
Chymase inhibitor-sensitive synthesis of endothelin-1 (1-31) by recombinant mouse mast cell protease 4 and human chymase.
(2015). Biochemical Pharmacology, vol. 94, ss. 91-100 DOI -
Ctr2 Regulates Mast Cell Maturation by Affecting the Storage and Expression of Tryptase and Proteoglycans.
(2015). Journal of Immunology, vol. 195, ss. 3654-3664 DOI -
Nuclear Receptor 4a3 (Nr4a3) Regulates Murine Mast Cell Responses and Granule Content.
(2014). PLOS ONE, vol. 9 DOI -
Proteolytic Histone Modification by Mast Cell Tryptase, a Serglycin Proteoglycan-dependent Secretory Granule Protease.
(2014). Journal of Biological Chemistry, vol. 289, ss. 7682-7690 DOI -
Mast cells are activated by Staphylococcus aureus in vitro but do not influence the outcome of intraperitoneal S. aureus infection in vivo.
(2014). Immunology, vol. 143, ss. 155-163 DOI -
Serglycin Proteoglycan Promotes Apoptotic versus Necrotic Cell Death in Mast Cells.
(2012). Journal of Biological Chemistry, vol. 287, ss. 18142-18152 DOI -
Altered storage of proteases in mast cells from mice lacking heparin: a possible role for heparin in carboxypeptidase A processing..
(2002). Biological Chemistry, vol. 383, ss. 793-801 -
Secretory granule proteases in rat mast cells: Cloning of 10 different serine proteases and a carboxypeptidase A from various rat mast cell populations.
(1997). Journal of Experimental Medicine, vol. 185, ss. 13-29 DOI