Publications
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Pervasive Selection for Clinically Relevant Resistance and Media Adaptive Mutations at Very Low Antibiotic Concentrations.
(2023). Molecular biology and evolution, . vol. 40 DOI -
Potential risks of treating bacterial infections with a combination of β-lactam and aminoglycoside antibiotics: A systematic quantification of antibiotic interactions in E. coli blood stream infection isolates.
(2022). EBioMedicine, vol. 78 DOI -
Antibiotic Minimal Selective Concentrations and Fitness Costs during Biofilm and Planktonic Growth.
(2022). mBio, . vol. 13 DOI -
Prevalence of colistin heteroresistance in carbapenem-resistant Pseudomonas aeruginosa and association with clinical outcomes in patients: an observational study.
(2022). Journal of Antimicrobial Chemotherapy, . vol. 77, ss. 793-798 DOI -
Low levels of tetracyclines select for a mutation that prevents the evolution of high-level resistance to tigecycline.
(2022). PLoS biology, . vol. 20 DOI -
The physiology and genetics of bacterial responses to antibiotic combinations.
(2022). Nature Reviews Microbiology, . vol. 20, ss. 478-490 DOI -
A Microfluidic Chip for Studies of the Dynamics of Antibiotic Resistance Selection in Bacterial Biofilms.
(2022). Frontiers in Cellular and Infection Microbiology, . vol. 12 DOI -
Modular 3D-Printed Peg Biofilm Device for Flexible Setup of Surface-Related Biofilm Studies.
(2022). Frontiers in Cellular and Infection Microbiology, . vol. 11 DOI -
An Effort Worth Making: A Qualitative Study of How Swedes Respond to Antibiotic Resistance.
(2021). Public Health Ethics, . vol. 14, ss. 1-11 DOI -
Selection of Resistant Bacteria in Mallards Exposed to Subinhibitory Concentrations of Ciprofloxacin in Their Water Environment.
(2021). Antimicrobial Agents and Chemotherapy, . vol. 65 DOI -
The chemotherapeutic drug methotrexate selects for antibiotic resistance.
(2021). EBioMedicine, . vol. 74 DOI -
Structure and mechanism of a phage-encoded SAM lyase revises catalytic function of enzyme family.
(2021). eLIFE, vol. 10 DOI -
A novel type of colistin resistance genes selected from random sequence space.
(2021). PLOS Genetics, . vol. 17 DOI -
The highly dynamic nature of bacterial heteroresistance impairs its clinical detection.
(2021). Communications Biology, . vol. 4 DOI -
Metabolic fitness landscapes predict the evolution of antibiotic resistance.
(2021). Nature Ecology & Evolution, . vol. 5, ss. 677-687 DOI -
A broad spectrum anti-bacterial peptide with an adjunct potential for tuberculosis chemotherapy.
(2021). Scientific Reports, . vol. 11 DOI -
Mechanisms and therapeutic potential of collateral sensitivity to antibiotics.
(2021). PLoS Pathogens, . vol. 17 DOI -
Preferences regarding antibiotic treatment and the role of antibiotic resistance: a discrete choice experiment.
(2020). International Journal of Antimicrobial Agents, vol. 56 DOI -
Antibiotic resistance: turning evolutionary principles into clinical reality.
(2020). FEMS Microbiology Reviews, vol. 44, ss. 171-188 DOI -
Antimicrobial Peptide Exposure Selects for Resistant and Fit Stenotrophomonas maltophilia Mutants That Show Cross-Resistance to Antibiotics.
(2020). mSphere, . vol. 5 DOI -
CombiANT: Antibiotic interaction testing made easy.
(2020). PLoS biology, . vol. 18 DOI -
Dynamics of Extensive Drug Resistance Evolution of Mycobacterium tuberculosis in a Single Patient During 9 Years of Disease and Treatment.
(2020). Journal of Infectious Diseases, . vol. 225, ss. 1011-1020 DOI -
Synonymous mutations in rpsT lead to ribosomal assembly defects that can be compensated by mutations in fis and rpoA.
(2020). Frontiers in Microbiology, vol. 11 DOI -
Mutational Pathways and Trade-Offs Between HisA and TrpF Functions: Implications for Evolution via Gene Duplication and Divergence.
(2020). Frontiers in Microbiology, vol. 11 DOI -
Mutations that increase expression of the EmrAB-TolC efflux pump confer increased resistance to nitroxoline in Escherichia coli.
(2020). Journal of Antimicrobial Chemotherapy, vol. 75, ss. 300-308 DOI -
Molecular mechanisms of collateral sensitivity to the antibiotic nitrofurantoin.
(2020). PLoS biology, . vol. 18 DOI -
Evolution of a New Function by Fusion between Phage DNA and a Bacterial Gene.
(2020). Molecular biology and evolution, . vol. 37, ss. 1329-1341 DOI -
Mechanisms and clinical relevance of bacterial heteroresistance.
(2019). Nature Reviews Microbiology, . vol. 17, ss. 479-496 DOI -
Definitions and guidelines for research on antibiotic persistence.
(2019). Nature Reviews Microbiology, . vol. 17, ss. 441-448 DOI -
Inhibition of translation termination by small molecules targeting ribosomal release factors.
(2019). Scientific Reports, . vol. 9 DOI -
De Novo Emergence of Peptides That Confer Antibiotic Resistance.
(2019). mBio, . vol. 10 DOI -
The high prevalence of antibiotic heteroresistance in pathogenic bacteria is mainly caused by gene amplification.
(2019). Nature Microbiology, vol. 4, ss. 504-514 DOI -
A portable epigenetic switch for bistable gene expression in bacteria.
(2019). Scientific Reports, . vol. 9 DOI -
Collateral sensitivity constrains resistance evolution of the CTX-M-15 beta-lactamase.
(2019). Nature Communications, . vol. 10 DOI -
Upregulation of PBP1B and LpoB in cysB Mutants Confers Mecillinam (Amdinocillin) Resistance in Escherichia coli.
(2019). Antimicrobial Agents and Chemotherapy, vol. 63 DOI -
Selection for novel metabolic capabilities in Salmonella enterica.
(2019). Evolution, vol. 73, ss. 990-1000 DOI -
Public awareness and individual responsibility needed for judicious use of antibiotics: a qualitative study of public beliefs and perceptions.
(2018). BMC Public Health, . vol. 18 DOI -
Occurrence of Yersinia rohdei among feral reindeer (Rangifer t. tarandus) and kelp gulls (Larus dominicanus) on the Sub-Antarctic island South Georgia..
(2018). Infection Ecology & Epidemiology, vol. 8 DOI -
A bacteriophage enzyme induces bacterial metabolic perturbation that confers a novel promiscuous function.
(2018). Nature Ecology & Evolution, . vol. 2, ss. 1321-1330 DOI -
Predicting mutant selection in competition experiments with ciprofloxacin-exposed Escherichia coli.
(2018). International Journal of Antimicrobial Agents, vol. 51, ss. 399-406 DOI -
Predictable Phenotypes of Antibiotic Resistance Mutations.
(2018). mBio, vol. 9 DOI -
No beneficial fitness effects of random peptides.
(2018). Nature Ecology & Evolution, vol. 2, ss. 1046-1047 DOI -
Genetic adaptation to growth under laboratory conditions in Escherichia coli and Salmonella enterica.
(2018). Frontiers in Microbiology, vol. 9 DOI -
Experimental Determination and Prediction of the Fitness Effects of Random Point Mutations in the Biosynthetic Enzyme HisA.
(2018). Molecular biology and evolution, vol. 35, ss. 704-718 DOI -
Cellular hysteresis as a principle to maximize the efficacy of antibiotic therapy..
(2018). Proceedings of the National Academy of Sciences of the United States of America, vol. 115, ss. 9767-9772 DOI -
Long-term carriage and rapid transmission of extended spectrum beta-lactamase-producing E. coli within a flock of Mallards in the absence of antibiotic selection.
(2018). Environmental Microbiology Reports, vol. 10, ss. 576-582 DOI -
Different adaptive strategies in E-coli populations evolving under macronutrient limitation and metal ion limitation.
(2018). BMC Evolutionary Biology, vol. 18 DOI -
Evolution of high-level resistance during low-level antibiotic exposure.
(2018). Nature Communications, vol. 9 DOI -
Pharmacokinetics and Pharmacodynamics of Fosfomycin and Its Activity against Extended-Spectrum-beta-Lactamase-, Plasmid-Mediated AmpC-, and Carbapenemase-Producing Escherichia coli in a Murine Urinary Tract Infection Model.
(2018). Antimicrobial Agents and Chemotherapy, . vol. 62 DOI -
Selection and Transmission of Antibiotic-Resistant Bacteria.
(2017). Microbiology Spectrum, vol. 5 5 DOI -
Antibiotic susceptibility testing in less than 30 min using direct single-cell imaging.
(2017). Proceedings of the National Academy of Sciences of the United States of America, vol. 114, ss. 9170-9175 DOI -
Transfer and Persistence of a Multi-Drug Resistance Plasmid in situ of the Infant Gut Microbiotain the Absence of Antibiotic Treatment.
(2017). Frontiers in Microbiology, . vol. 8 DOI -
Environmental and genetic modulation of the phenotypic expression of antibiotic resistance.
(2017). FEMS Microbiology Reviews, vol. 41, ss. 374-391 DOI -
Evolutionary Trajectories to Antibiotic Resistance.
(2017). Annual Review of Microbiology, vol. 71, ss. 579-596 DOI -
Functional Constraints on Replacing an Essential Gene with Its Ancient and Modern Homologs.
(2017). mBio, vol. 8 DOI -
Evolution of antibiotic resistance without antibiotic exposure.
(2017). Antimicrobial Agents and Chemotherapy, vol. 61 DOI -
Antimicrobial peptide exposure selects for Staphylococcus aureus resistance to human defence peptides.
(2017). Journal of Antimicrobial Chemotherapy, . vol. 72, ss. 115-127 DOI -
Variation in Mutational Robustness between Different Proteins and the Predictability of Fitness Effects.
(2017). Molecular biology and evolution, . vol. 34, ss. 408-418 DOI -
Resistance to the Cyclotide Cycloviolacin O2 in Salmonella enterica Caused by Different Mutations That Often Confer Cross-Resistance or Collateral Sensitivity to Other Antimicrobial Peptides.
(2017). Antimicrobial Agents and Chemotherapy, vol. 61 DOI -
Structural and functional innovations in the real-time evolution of new (βα)8 barrel enzymes.
(2017). Proceedings of the National Academy of Sciences of the United States of America, vol. 114, ss. 4727-4732 DOI -
Can a pharmacokinetic/pharmacodynamic (PKPD) model be predictive across bacterial densities and strains?: External evaluation of a PKPD model describing longitudinal in vitro data.
(2017). Journal of Antimicrobial Chemotherapy, . vol. 72, ss. 3108-3116 DOI -
Duplication-Insertion Recombineering: a fast and scar-free method for efficient transfer of multiple mutations in bacteria.
(2017). Nucleic Acids Research, . vol. 45 DOI Download fulltext -
Genome Dynamics of Escherichia coli during Antibiotic Treatment: Transfer, Loss, and Persistence of Genetic Elements In situ of the Infant Gut.
(2017). Frontiers in Cellular and Infection Microbiology, . vol. 7 DOI -
Prediction of antibiotic resistance: time for a new preclinical paradigm?.
(2017). Nature Reviews Microbiology, vol. 15, ss. 688-695 DOI -
Reversion of High-level Mecillinam Resistance to Susceptibility in Escherichia coli During Growth in Urine..
(2017). EBioMedicine, vol. 23, ss. 111-118 DOI -
Combinations of mutations in envZ, ftsI, mrdA, acrB and acrR can cause high-level carbapenem resistance in Escherichia coli.
(2016). Journal of Antimicrobial Chemotherapy, vol. 71, ss. 1188-1198 DOI -
Mechanisms and consequences of bacterial resistance to antimicrobial peptides.
(2016). Drug resistance updates, vol. 26, ss. 43-57 DOI -
Nonmutational compensation of the fitness cost of antibiotic resistance in mycobacteria by overexpression of tlyA rRNA methylase.
(2016). RNA, vol. 22, ss. 1836-1843 DOI -
Unstable tandem gene amplification generates heteroresistance (variation in resistance within a population) to colistin in Salmonella enterica.
(2016). Molecular Microbiology, vol. 102, ss. 274-289 DOI -
Compensating the fitness costs of synonymous mutations.
(2016). Molecular biology and evolution, vol. 33, ss. 1461-1477 DOI -
Fitness of Escherichia coli mutants with reduced susceptibility to tigecycline.
(2016). Journal of Antimicrobial Chemotherapy, vol. 71, ss. 1307-1313 DOI -
Potential of tetracycline resistance proteins to evolve tigecycline resistance.
(2016). Antimicrobial Agents and Chemotherapy, vol. 60, ss. 789-796 DOI -
Bacterial Resistance To A Cyclic Antimicrobial Peptide.
(2016). Journal of Peptide Science, vol. 22, ss. S180-S180 DOI -
Indirect resistance to several classes of antibiotics in cocultures with resistant bacteria expressing antibiotic-modifying or -degrading enzymes.
(2016). Journal of Antimicrobial Chemotherapy, vol. 71, ss. 100-110 DOI -
Improving predictions of the risk of resistance development against new and old antibiotics.
(2015). Clinical Microbiology and Infection, vol. 21, ss. 894-898 DOI -
Evolution of New Functions De Novo and from Preexisting Genes.
(2015). Cold Spring Harbor Perspectives in Biology, vol. 7 DOI -
Structure of AadA from Salmonella enterica: a monomeric aminoglycoside (3'')(9) adenyltransferase.
(2015). Acta Crystallographica Section D, vol. 71, ss. 2267-2277 DOI -
Evolutionary consequences of drug resistance: shared principles across diverse targets and organisms.
(2015). Nature reviews genetics, vol. 16, ss. 459-471 DOI -
A mechanism-based pharmacokinetic/pharmacodynamic model allows prediction of antibiotic killing from MIC values for WT and mutants.
(2015). Journal of Antimicrobial Chemotherapy, vol. 70, ss. 3051-3060 DOI -
Amelioration of the Fitness Costs of Antibiotic Resistance Due To Reduced Outer Membrane Permeability by Upregulation of Alternative Porins.
(2015). Molecular biology and evolution, vol. 32, ss. 3252-3263 DOI -
Fitness of Salmonella mutants resistant to antimicrobial peptides.
(2015). Journal of Antimicrobial Chemotherapy, vol. 70, ss. 432-440 DOI -
A General Method for Rapid Determination of Antibiotic Susceptibility and Species in Bacterial Infections.
(2015). Journal of Clinical Microbiology, vol. 53, ss. 425-432 DOI -
Amdinocillin (Mecillinam) Resistance Mutations in Clinical Isolates and Laboratory-Selected Mutants of Escherichia coli.
(2015). Antimicrobial Agents and Chemotherapy, vol. 59, ss. 1723-1732 DOI -
High Fitness Costs and Instability of Gene Duplications Reduce Rates of Evolution of New Genes by Duplication-Divergence Mechanisms.
(2014). Molecular biology and evolution, vol. 31, ss. 1526-1535 DOI -
Microbiological effects of sublethal levels of antibiotics.
(2014). Nature Reviews Microbiology, vol. 12, ss. 465-478 DOI -
Selection of a multidrug resistance plasmid by sublethal levels of antibiotics and heavy metals.
(2014). mBio, vol. 5, ss. e01918-14- DOI -
Minor Fitness Costs in an Experimental Model of Horizontal Gene Transfer in Bacteria.
(2014). Molecular biology and evolution, vol. 31, ss. 1220-1227 DOI -
Selection of Orphan Rhs Toxin Expression in Evolved Salmonella enterica Serovar Typhimurium.
(2014). PLOS Genetics, vol. 10, ss. e1004255- DOI -
Characterization of Resitant Mutants Points Towards Mechanism of Action of Cyclotides.
(2014). Journal of Peptide Science, vol. 20, ss. S108-S109 -
Resistance to beta-Lactam Antibiotics Conferred by Point Mutations in Penicillin-Binding Proteins PBP3, PBP4 and PBP6 in Salmonella enterica.
(2014). PLOS ONE, vol. 9, ss. e97202- DOI -
Influence of acquired β-lactamases on the evolution of spontaneous carbapenem resistance in Escherichia coli.
(2013). Journal of Antimicrobial Chemotherapy, vol. 68, ss. 51-59 DOI -
Pathoadaptive Mutations in Salmonella enterica Isolated after Serial Passage in Mice.
(2013). PLOS ONE, vol. 8, ss. e70147- DOI -
Fitness Costs of Synonymous Mutations in the rpsT Gene Can Be Compensated by Restoring mRNA Base Pairing.
(2013). PLOS ONE, vol. 8, ss. e63373- DOI -
Mechanisms and fitness costs of tigecycline resistance in Escherichia coli.
(2013). Journal of Antimicrobial Chemotherapy, vol. 68, ss. 2809-2819 DOI -
Mechanisms and Fitness Costs of Resistance to Antimicrobial Peptides LL-37, CNY100HL and Wheat Germ Histones.
(2013). PLOS ONE, vol. 8, ss. e68875- DOI -
Lon protease inactivation, or translocation of the lon gene, potentiate bacterial evolution to antibiotic resistance.
(2013). Molecular Microbiology, vol. 90, ss. 1233-1248 DOI -
Evolution of Broad Spectrum beta-Lactam Resistance in an Engineered Metallo-beta-lactamase.
(2013). Journal of Biological Chemistry, vol. 288, ss. 2314-2324 DOI -
Evolution of antibiotic resistance at non-lethal drug concentrations..
(2012). Drug resistance updates, vol. 15, ss. 162-172 DOI -
Selection of resistance at lethal and non-lethal antibiotic concentrations.
(2012). Current Opinion in Microbiology, vol. 15, ss. 555-560 DOI -
Selection-driven genome reduction in bacteria.
(2012). PLOS genetics, vol. 8, ss. e1002787- DOI -
Real-Time Evolution of New Genes by Innovation, Amplification, and Divergence.
(2012). Science, vol. 338, ss. 384-387 DOI -
Poxvirus Use a "Gene Accordion" to Tune Out Host Defenses.
(2012). Cell, vol. 150, ss. 671-672 DOI -
Transfer of an Escherichia coli ST131 multiresistance cassette has created a Klebsiella pneumoniae-specific plasmid associated with a major nosocomial outbreak.
(2012). Journal of Antimicrobial Chemotherapy, vol. 67, ss. 74-83 DOI -
Genome-Wide Detection of Spontaneous Chromosomal Rearrangements in Bacteria.
(2012). PLOS ONE, vol. 7, ss. e42639- DOI -
Compensatory mutations in agrC partly restore fitness in vitro to peptide deformylase inhibitor-resistant Staphylococcus aureus.
(2012). Journal of Antimicrobial Chemotherapy, vol. 67, ss. 1835-1842 DOI -
Evolving promiscuously.
(2011). Proceedings of the National Academy of Sciences of the United States of America, vol. 108, ss. 1199-1200 DOI -
Persistence of antibiotic resistance in bacterial populations.
(2011). FEMS Microbiology Reviews, vol. 35, ss. 901-911 DOI -
Selection of Resistant Bacteria at Very Low Antibiotic Concentrations.
(2011). PLoS pathogens, vol. 7, ss. e1002158- DOI -
Activation of cryptic aminoglycoside resistance in Salmonella enterica.
(2011). Molecular Microbiology, vol. 80, ss. 1464-1478 DOI -
Beyond serial passages: new methods for predicting the emergence of resistance to novel antibiotics.
(2011). Current opinion in pharmacology (Print), vol. 11, ss. 439-445 DOI -
Dynamics of Antibiotic Resistant Mycobacterium tuberculosis during Long-Term Infection and Antibiotic Treatment.
(2011). PLOS ONE, vol. 6, ss. e21147- -
Activation of initiation factor 2 by ligands and mutations for rapid docking of ribosomal subunits.
(2011). EMBO Journal, vol. 30, ss. 289-301 DOI -
Escape from growth restriction in small colony variants of Salmonella typhimurium by gene amplification and mutation.
(2011). Molecular Microbiology, vol. 79, ss. 305-315 DOI -
PEG-stabilized lipid disks as carriers for amphiphilic antimicrobial peptides.
(2011). Journal of Controlled Release, vol. 156, ss. 323-328 DOI -
Antibiotic resistance and its cost: is it possible to reverse resistance?.
(2010). Nature Reviews Microbiology, vol. 8, ss. 260-271 DOI -
The origin of mutants under selection: Interactions of mutation, growth and selection.
(2010). I Böck et al (red.) EcoSal - Escherichia coli and Salmonella: cellular and molecular biology Washington, DC: ASM Press. DOI -
Biological roles of translesion synthesis DNA polymerases in eubacteria.
(2010). Molecular Microbiology, vol. 77, ss. 540-548 DOI -
Adventures with mutation and selection in beehive and cow country.
(2010). I Maloy, S., Hughes, K.T. and Casadesus, J (red.) The Lure of Bacterial Genetics, Washington, DC: ASM Press. ss. 245-253 -
Rates and Mechanisms of Resistance Development in Mycobacterium tuberculosis to a Novel Diarylquinoline ATP Synthase Inhibitor.
(2010). Antimicrobial Agents and Chemotherapy, vol. 54, ss. 1022-1028 DOI -
Effect of the translesion DNA polymerases, endonucleases and RpoS on mutation rates in Salmonella typhimurium.
(2010). Genetics, vol. 185, ss. 783-795 DOI -
The Tandem Inversion Duplication in Salmonella enterica: Selection Drives Unstable Precursors to Final Mutation Types.
(2010). Genetics, vol. 185, ss. 65-80 DOI -
Mutational robustness of ribosomal protein genes.
(2010). Science, vol. 330, ss. 825-827 DOI -
Compensatory gene amplification restores fitness after inter-species gene replacements.
(2010). Molecular Microbiology, vol. 75, ss. 1078-1089 DOI -
Amplification of the Gene for Isoleucyl-tRNA Synthetase Facilitates Adaptation to the Fitness Cost of Mupirocin Resistance in Salmonella enterica.
(2010). Genetics, vol. 185, ss. 305-312 DOI -
Mechanisms and physiological effects of protamine resistance in Salmonella enterica serovar Typhimurium LT2.
(2010). Journal of Antimicrobial Chemotherapy, vol. 65, ss. 876-887 DOI -
The cyclotide cycloviolacin O2 from Viola odorata has potent bactericidal activity against Gram-negative bacteria.
(2010). Journal of Antimicrobial Chemotherapy, vol. 65, ss. 1964-1971 DOI -
Directed mutagenesis of Mycobacterium smegmatis 16S rRNA to reconstruct the in-vivo evolution of aminoglycoside resistance in Mycobacterium tuberculosis.
(2010). Molecular Microbiology, vol. 77, ss. 830-40 DOI -
Little evidence for reversibility of trimethoprim resistance after a drastic reduction in trimethoprim use.
(2010). Journal of Antimicrobial Chemotherapy, . vol. 65, ss. 350-360 DOI -
Ribosomes lacking protein S20 are defective in mRNA binding and subunit association.
(2010). Journal of Molecular Biology, vol. 397, ss. 767-776 DOI -
Error-prone initiation factor 2 mutations reduce the fitness cost of antibiotic resistance.
(2010). Molecular Microbiology, . vol. 75, ss. 1299-1313 DOI -
Gene amplification and adaptive evolution in bacteria.
(2009). Annual Review of Genetics, vol. 43, ss. 167-195 DOI -
A multi-type branching model with varying environment for bacterial dynamics with postantibiotic effect.
(2009). Journal of Theoretical Biology, vol. 256, ss. 58-64 DOI -
Translesion DNA polymerases are required for spontaneous deletion formation in Salmonella typhimurium.
(2009). Proceedings of the National Academy of Sciences of the United States of America, vol. 106, ss. 10248-10253 DOI -
The fitness cost of streptomycin resistance depends on rpsL mutation, carbon source and RpoS (sigmaS).
(2009). Genetics, vol. 183, ss. 539-546 DOI -
Evolution of new gene functions: simulation and analysis of the amplification model..
(2009). Genetica, vol. 135, ss. 309-324 DOI -
Bacterial gene amplification: implications for the evolution of antibiotic resistance.
(2009). Nature Reviews Microbiology, vol. 7, ss. 578-588 DOI -
Contribution of gene amplification to evolution of increased antibiotic resistance in Salmonella typhimurium.
(2009). Genetics, vol. 182, ss. 1183-1195 DOI -
Genetic analysis of colistin resistance in Salmonella enterica serovar Typhimurium.
(2009). Antimicrobial Agents and Chemotherapy, vol. 53, ss. 2298-2305 DOI -
Shrinking Bacterial Genomes: Former skeptics recognize that the genomes of microbial parasites and symbionts are subject to dynamic downsizing.
(2008). Microbe, Washington: American Society for Microbiology. vol. 3, ss. 124-130 -
Effects of antibiotic resistance on bacterial fitness, virulence and transmission.
(2008). I Baquero, Fernando Nombela, Cesar Cassell, Gail H. (red.) Evolutionary biology of bacterial and fungal pathogens, Washington DC: ASM Press. ss. 307-318 -
Whole-genome mutational biases in bacteria.
(2008). Proceedings of the National Academy of Sciences of the United States of America, vol. 105, ss. 17878-83 DOI -
The first major extended-spectrum beta-lactamase outbreak in Scandinavia was caused by clonal spread of a multiresistant Klebsiella pneumoniae producing CTX-M-15.
(2008). Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS), vol. 116, ss. 302-8 DOI -
Restored fitness leads to long-term persistence of resistant Bacteroides strains in the human intestine.
(2008). Anaerobe, vol. 14, ss. 157-160 DOI -
Mechanism and fitness costs of PR-39 resistance in Salmonella enterica serovar Typhimurium LT2.
(2008). Antimicrobial Agents and Chemotherapy, vol. 52, ss. 2734-2741 DOI -
Nitrofurantoin resistance mechanism and fitness cost in Escherichia coli.
(2008). Journal of Antimicrobial Chemotherapy, vol. 62, ss. 495-503 DOI -
The Biological Cost of Antibiotic resistance.
(2007). I Enzyme-Mediated Resistance to Antibiotics, ss. 339-348 -
Ohno's dilemma: evolution of new genes under continuous selection.
(2007). Proceedings of the National Academy of Sciences of the United States of America, vol. 104, ss. 17004-17009 DOI -
Compensatory Evolution Reveals Functional Interactions between Ribosomal Proteins S12, L14 and L19.
(2007). Journal of Molecular Biology, vol. 366, ss. 207-215 DOI -
Predicting antibiotic resistance.
(2007). Nature Reviews Microbiology, vol. 5, ss. 958-965 DOI -
Multiple mechanisms to ameliorate the fitness burden of mupirocin resistance in Salmonella typhimurium.
(2007). Molecular Microbiology, vol. 64, ss. 1038-1048 DOI -
Caenorhabditis elegans as a model to determine fitness of antibiotic-resistant Salmonella enterica serovar typhimurium.
(2007). Antimicrobial Agents and Chemotherapy, vol. 51, ss. 766-769 DOI -
Antibiotic treatment in vitro of phenotypically tolerant bacterial populations.
(2007). Journal of Antimicrobial Chemotherapy, vol. 59, ss. 254-263 DOI -
The biological cost of mutational antibiotic resistance: any practical conclusions?.
(2006). Curr Opin Microbiol, vol. 9, ss. 461-5 -
Multiple pathways of selected gene amplification during adaptive mutation.
(2006). Proceedings of the National Academy of Sciences of the United States of America, vol. 103, ss. 17319-17324 DOI -
Reducing the fitness cost of antibiotic resistance by amplification of initiator tRNA genes.
(2006). Proceedings of the National Academy of Sciences of the United States of America, vol. 103, ss. 6976-6981 DOI -
Origin of mutations under selection: the adaptive mutation controversy..
(2006). Annu Rev Microbiol, vol. 60, ss. 477-501 -
Drug resistance and fitness in Mycobacterium tuberculosis infection..
(2005). J Infect Dis, vol. 191, ss. 823-4; author reply 824 -
Reduction of the fitness burden of quinolone resistance in Pseudomonas aeruginosa.
(2005). Journal of Antimicrobial Chemotherapy, vol. 55, ss. 22-30 DOI -
Establishment of a superficial skin infection model in mice by using Staphylococcus aureus and Streptococcus pyogenes.
(2005). Antimicrobial Agents and Chemotherapy, vol. 49, ss. 3435-3441 DOI -
Slow genetic divergence of Helicobacter pylori strains during long-term colonization.
(2005). Infection and Immunity, vol. 73, ss. 4818-4822 DOI -
Genomic buffering mitigates the effects of deleterious mutations in bacteria.
(2005). Nature Genetics, vol. 37, ss. 1376-1379 DOI -
Bacterial genome size reduction by experimental evolution.
(2005). Proceedings of the National Academy of Sciences of the United States of America, vol. 102, ss. 12112-12116 DOI -
Pharmacodynamic model to describe the concentration-dependent selection of cefotaxime-resistant Escherichia coli..
(2005). Antimicrob Agents Chemother, vol. 49, ss. 5081-91 -
Pharmacodynamic model to describe the concentration-dependent selection of cefotaxime-resistant Escherichia coli.
(2005). Antimicrobial Agents and Chemotherapy, vol. 49, ss. 5081-5091 -
Persistence of resistant Staphylococcus epidermidis after single course of clarithromycin.
(2005). Emerging Infectious Diseases, vol. 11, ss. 1389-1393 -
Polymorphic mutation frequencies in Escherichia coli: emergence of weak mutators in clinical isolates.
(2004). Journal of Bacteriology, vol. 186, ss. 5538-5542 DOI -
Adaptation to the deleterious effects of antimicrobial drug resistance mutations by compensatory evolution.
(2004). Research in Microbiology, vol. 155, ss. 360-369 DOI -
Effect of rpoB mutations conferring rifampin resistance on fitness of Mycobacterium tuberculosis.
(2004). Antimicrobial Agents and Chemotherapy, vol. 48, ss. 1289-1294 -
Experimental adaptation of Salmonella typhimurium to mice.
(2004). Genetics, vol. 168, ss. 1119-1130 DOI -
The amplification model for adaptive mutation: simulations and analysis.
(2004). Genetics, vol. 169, ss. 1105-1115 DOI -
Amplification-mutagenesis: how growth under selection contributes to the origin of genetic diversity and explains the phenomenon of adaptive mutation.
(2004). Research in Microbiology, vol. 155, ss. 342-351 DOI -
Adaptive mutation: how growth under selection stimulates Lac(+) reversion by increasing target copy number.
(2004). Journal of Bacteriology, vol. 186, ss. 4855-4860 DOI -
Rebuttal: adaptive mutation in Escherichia coli (Foster).
(2004). Journal of Bacteriology, vol. 186, ss. 4854-4854 DOI -
Rebuttal: adaptive point mutation (Rosenberg and Hastings).
(2004). Journal of Bacteriology, vol. 186, ss. 4844- DOI -
Comparative proteome analysis of Mycobacterium tuberculosis grown under aerobic and anaerobic conditions.
(2004). Microbiology, vol. 150, ss. 3821-3829 DOI -
Bacteria with increased mutation frequency and antibiotic resistance are enriched in the commensal flora of patients with high antibiotic usage.
(2003). Journal of Antimicrobial Chemotherapy, vol. 52, ss. 645-650 DOI -
The NudA protein in the gastric pathogen Helicobacter pylori is an ubiquitous and constitutively expressed dinucleoside polyphosphate hydrolase.
(2003). Journal of Biological Chemistry, vol. 278, ss. 12574-12578 DOI -
Long-term persistence of resistant Enterococcus species after antibiotics to eradicate Helicobacter pylori.
(2003). Ann Intern Med, vol. 139, ss. 483-7 -
Long-term persistence of resistant Enterococcus species after antibiotics to eradicate Helicobacter pylori.
(2003). Annals of Internal Medicine, vol. 139, ss. 483-487 -
Mutation frequency and biological cost of resistance in Helicobacter pylori..
(2001). Proc Natl Acad Sci U S A, vol. 98, ss. 14607-12 -
Muller's ratchet decreases fitness of a DNA-based microbe.
(1996). Proceedings of the National Academy of Sciences of the United States of America, vol. 93, ss. 906-907