Publications

Tripeptidyl-peptidase II: Update on an oldie that still counts.
Tomkinson, B. (2019). Biochimie, vol. 166, ss. 27-37 DOI
TPP2 mutation associated with sterile brain inflammation mimicking MS.
Reinthaler, E., Graf, E., Zrzavy, T., Wieland, T., Hotzy, C. et al. (2018). NEUROLOGY-GENETICS, vol. 4 4 DOI
Mutations in the gene tripeptidyl peptidase II (TPP2) and multiple sclerosis.
Reinthaler, E., Graf, E., Zrzavy, T., Wieland, T., Hotzy, C. et al. (2016). Multiple Sclerosis Journal, . vol. 22, ss. 849-849
Tripeptidyl Peptidase II Mediates Levels of Nuclear Phosphorylated ERK1 and ERK2.
Wiemhoefer, A., Stargardt, A., van der Linden, W., Renner, M., van Kesteren, R. et al. (2015). Molecular & Cellular Proteomics, vol. 14, ss. 2177-2193 DOI
TPPII, MYBBP1A and CDK2 form a protein–protein interaction network.
Nahálková, J., Tomkinson, B. (2014). Archives of Biochemistry and Biophysics, . vol. 564, ss. 128-135 DOI
Characterization of the endopeptidase activity of tripeptidyl-peptidase II.
Eklund, S., Dogan, J., Jemth, P., Kalbacher, H., Tomkinson, B. (2012). Biochemical and Biophysical Research Communications - BBRC, vol. 424, ss. 503-507 DOI
Exploring the active site of tripeptidyl-peptidase II through studies of pH dependence of reaction kinetics.
Eklund, S., Lindås, A., Hamnevik, E., Widersten, M., Tomkinson, B. (2012). Biochimica et Biophysica Acta - Proteins and Proteomics, vol. 1824, ss. 561-570 DOI
Structure, Function and Evolution of a Giant Enzyme, Tripeptidyl-Peptidase II.
Eklund, S., Tomkinson, B. (2012). I Isamu Chiba & Takao Kamio (red.) Serine proteases, . ss. 55-70 Download fulltext
Tripeptidyl-peptidase II.
Tomkinson, B., Eklund, S. (2012). I Neil D. Rawlings & Guy S. Salvesen (red.) Handbook of Proteolytic Enzymes volume 1, . ss. 3325-3331 DOI
Antigen processing by nardilysin and thimet oligopeptidase generates cytotoxic T cell epitopes.
Kessler, J., Khan, S., Seifert, U., Le Gall, S., Chow, K. et al. (2010). Nature Immunology, vol. 12, ss. 45-53 DOI
Development, evaluation and application of tripeptidyl-peptidase II sequence signatures.
Eriksson, S., Gutierrez Arenas, O., Bjerling, P., Tomkinson, B. (2009). Archives of Biochemistry and Biophysics, vol. 484, ss. 39-45 DOI
Investigation of a role for Glu-331 and Glu-305 in substrate binding of tripeptidyl-peptidase II.
Lindås, A., Eriksson, S., Jozsa, E., Tomkinson, B. (2008). Biochimica et Biophysica Acta - Proteins and Proteomics, vol. 1784, ss. 1899-1907 DOI
Characterization of the promoter of the gene encoding human tripeptidyl-peptidase II and identification of upstream silencer elements.
Lindås, A., Tomkinson, B. (2007). Gene, vol. 393, ss. 62-69 DOI
Overlapping regional distribution of CCK and TPPII mRNAs in Cynomolgus monkey brain and correlated levels in human cerebral cortex (BA 10).
Radu, D., Tomkinson, B., Zachrisson, O., Weber, G., de Belleroche, J. et al. (2006). Brain Research, vol. 1104, ss. 175-182 DOI
Identification and characterization of the promoter for the gene encoding human tripeptidyl-peptidase II..
Lindås, A., Tomkinson, B. (2005). Gene, vol. 345, ss. 249-57
Mitotic infidelity and centrosome duplication errors in cells overexpressing tripeptidyl-peptidase II..
Stavropoulou, V., Xie, J., Henriksson, M., Tomkinson, B., Imreh, S. et al. (2005). Cancer Res, vol. 65, ss. 1361-8
Tripeptidyl-peptidase II: a multi-purpose peptidase..
Tomkinson, B., Lindås, A. (2005). Int J Biochem Cell Biol, vol. 37, ss. 1933-7
Tripeptidyl-peptidase II.
Tomkinson, B. (2004). I Handbook of proteolytic enzymes, . ss. 1882-1885
Identification of the catalytic triad in tripeptidyl-peptidase II trough site-directed mutagenesis.
Hibli, H., Jozsa, E., Tomkinson, B. (2002). Biochimica et Biophysica Acta, vol. 1601 1601, ss. 149 149-154 154
The insert within the catalytic domain of tripeptidyl-peptidase II is important for the formation of the active complex.
Tomkinson, B., Ni Laoi, B., Wellington, K. (2002). European Journal of Biochemistry, vol. 269, ss. 1438-1443
Tripeptidyl-peptidase II expression and activity are increased in skeletal muscle during sepsis.
Wray, C., Tomkinson, B., Robb, B., Hasselgren, P. (2002). Biochemical and Biophysical Research Communications, vol. 296 296, ss. 41 41-47 47
Association and dissociation of the tripeptidyl-peptidase II complex as a way of regulating the enzyme activity.
Tomkinson, B. (2000). ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, . vol. 376, ss. 275-280
Tripeptidyl peptidases: enzymes that count..
Tomkinson, B. (1999). Trends Biochem Sci, vol. 24, ss. 355-9
Distribution of tripeptidyl-peptidase II in the central nervous system of rat.
Tomkinson, B., Nyberg, F. (1995). Neurochemical Research, vol. 20, ss. 1443-1447 DOI