Publications

Neutrophil extracellular traps in the pathology of cancer and other inflammatory diseases.
Herre, M., Cedervall, J., Mackman, N., Olsson, A. (2023). Physiological Reviews, . vol. 103, ss. 277-312 DOI
Targeting Glioblastoma-Associated Macrophages for Photodynamic Therapy Using AGuIX^®-Design Nanoparticles.
Lerouge, L., Gries, M., Chateau, A., Daouk, J., Lux, F. et al. (2023). Pharmaceutics, . vol. 15 DOI
Quantitative Analysis of the Transcriptome of Two Commonly Used Human Monocytic Cell Lines-THP-1 and Mono Mac 6-Reveals Their Arrest during Early Monocyte/Neutrophil Differentiation.
Akula, S., Lara, S., Olsson, A., Hellman, L. (2022). International Journal of Molecular Sciences, . vol. 23 DOI
Vaccination against galectin-1 promotes cytotoxic T-cell infiltration in melanoma and reduces tumor burden.
Femel, J., van Hooren, L., Herre, M., Cedervall, J., Saupe, F. et al. (2022). Cancer Immunology and Immunotherapy, . vol. 71, ss. 2029-2040 DOI
Chicken cathepsin G-like - A highly specific serine protease with a peculiar tryptase specificity expressed by chicken thrombocytes.
Fu, Z., Akula, S., Olsson, A., Hellman, L. (2022). Developmental and Comparative Immunology, . vol. 129 DOI
Quantitative In-Depth Transcriptome Analysis Implicates Peritoneal Macrophages as Important Players in the Complement and Coagulation Systems.
Paivandy, A., Akula, S., Lara, S., Fu, Z., Olsson, A. et al. (2022). International Journal of Molecular Sciences, . vol. 23 DOI
Mast cell tryptase potentiates neutrophil extracellular trap formation.
Pejler, G., Alanazi, S., Grujic, M., Adler, J., Olsson, A. et al. (2022). Journal of Innate Immunity, . vol. 14, ss. 433-446 DOI
Extended cleavage specificity of a Chinese alligator granzyme B homologue, a strict Glu-ase in contrast to the mammalian Asp-ases.
Ryu, J., Fu, Z., Akula, S., Olsson, A., Hellman, L. (2022). Developmental and Comparative Immunology, . vol. 128 DOI
Inflammation and neutrophil extracellular traps in cerebral cavernous malformation (vol 79, 206, 2022).
Yau, A., Globisch, M., Onyeogaziri, F., Conze, L., Smith, R. et al. (2022). Cellular and Molecular Life Sciences (CMLS), . vol. 79 DOI
Inflammation and neutrophil extracellular traps in cerebral cavernous malformation.
Yau, A., Globisch, M., Onyeogaziri, F., Conze, L., Smith, R. et al. (2022). Cellular and Molecular Life Sciences (CMLS), . vol. 79 DOI
Platelet-Derived PDGFB Promotes Recruitment of Cancer-Associated Fibroblasts, Deposition of Extracellular Matrix and Tgf beta Signaling in the Tumor Microenvironment.
Zhang, Y., Doulabi, E., Herre, M., Cedervall, J., Qiao, Q. et al. (2022). Cancers, . vol. 14 DOI
Mast Cells and Basophils in the Defense against Ectoparasites: Efficient Degradation of Parasite Anticoagulants by the Connective Tissue Mast Cell Chymases.
Fu, Z., Akula, S., Olsson, A., Kervinen, J., Hellman, L. (2021). International Journal of Molecular Sciences, . vol. 22 DOI
Illustrated State-of-the-Art Capsules of the ISTH 2020 Congress.
Ariens, R., Becattini, C., Bender, M., Bergmeier, W., Castoldi, E. et al. (2020). RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS, . vol. 4, ss. 680-713 DOI
Specific targeting of PDGFR beta in the stroma inhibits growth and angiogenesis in tumors with high PDGF-BB expression.
Tsioumpekou, M., Cunha, S., Ma, H., Åhgren, A., Cedervall, J. et al. (2020). Theranostics, . vol. 10, ss. 1122-1135 DOI
Platelet-Specific PDGFB Ablation Impairs Tumor Vessel Integrity and Promotes Metastasis.
Zhang, Y., Cedervall, J., Hamidi, A., Herre, M., Viitaniemi, K. et al. (2020). Cancer Research, . vol. 80, ss. 3345-3358 DOI
TANK-binding kinase 1 is a mediator of platelet-induced EMT in mammary carcinoma cells.
Zhang, Y., Valsala Madhavan Unnithan, R., Hamidi, A., Caja, L., Saupe, F. et al. (2019). The FASEB Journal, vol. 33, ss. 7822-7832 DOI
Platelets, NETs and cancer.
Cedervall, J., Hamidi, A., Olsson, A. (2018). Thrombosis Research, . vol. 164, ss. S148-S152 DOI
Trametinib prevents mesothelial-mesenchymal transition and ameliorates abdominal adhesion formation.
Macarak, E., Lotto, C., Koganti, D., Jin, X., Wermuth, P. et al. (2018). Journal of Surgical Research, . vol. 227, ss. 198-210 DOI
Consensus guidelines for the use and interpretation of angiogenesis assays.
Nowak-Sliwinska, P., Alitalo, K., Allen, E., Anisimov, A., Aplin, A. et al. (2018). Angiogenesis, . vol. 21, ss. 425-532 DOI
The pro-inflammatory role of platelets in cancer.
Olsson, A., Cedervall, J. (2018). Platelets, . vol. 29, ss. 569-573 DOI
Pharmacological targeting of peptidylarginine deiminase 4 prevents cancer-associated kidney injury in mice..
Cedervall, J., Dragomir, A., Saupe, F., Zhang, Y., Ärnlöv, J. et al. (2017). Oncoimmunology, vol. 6 DOI
Development of a novel therapeutic vaccine carrier that sustains high antibody titers against several targets simultaneously.
Saupe, F., Reichel, M., Huijbers, E., Femel, J., Markgren, P. et al. (2017). The FASEB Journal, vol. 31, ss. 1204-1214 DOI
Tumor-induced neutrophil extracellular traps-drivers of systemic inflammation and vascular dysfunction.
Cedervall, J., Dimberg, A., Olsson, A. (2016). Oncoimmunology, vol. 5 DOI
Immunity Gone Astray - NETs in Cancer.
Cedervall, J., Olsson, A. (2016). Trends in Cancer, vol. 2, ss. 633-634 DOI
Tumor-Induced NETosis as a Risk Factor for Metastasis and Organ Failure.
Cedervall, J., Zhang, Y., Olsson, A. (2016). Cancer Research, vol. 76, ss. 4311-4315 DOI
NETosis in Cancer - Platelet-Neutrophil Crosstalk Promotes Tumor-Associated Pathology.
Olsson, A., Cedervall, J. (2016). Frontiers in Immunology, vol. 7 DOI
Targeting Serglycin Prevents Metastasis in Murine Mammary Carcinoma.
Roy, A., Femel, J., Huijbers, E., Spillmann, D., Larsson, E. et al. (2016). PLOS ONE, vol. 11 DOI
Ras and TGF-beta signaling enhance cancer progression by promoting the Delta Np63 transcriptional program.
Vasilaki, E., Morikawa, M., Koinuma, D., Mizutani, A., Hirano, Y. et al. (2016). Science Signaling, vol. 9 DOI
Tumor-Induced Local and Systemic Impact on Blood Vessel Function.
Cedervall, J., Dimberg, A., Olsson, A. (2015). Mediators of Inflammation DOI
Neutrophil Extracellular Traps Accumulate in Peripheral Blood Vessels and Compromise Organ Function in Tumor-Bearing Animals.
Cedervall, J., Zhang, Y., Huang, H., Zhang, L., Femel, J. et al. (2015). Cancer Research, vol. 75, ss. 2653-2662 DOI
Vaccines targeting self-antigens: mechanisms and efficacy-determining parameters.
Saupe, F., Huijbers, E., Hein, T., Femel, J., Cedervall, J. et al. (2015). The FASEB Journal, vol. 29, ss. 3253-3262 DOI
CCL2 and CCL5 Are Novel Therapeutic Targets for Estrogen-Dependent Breast Cancer.
Svensson, S., Abrahamsson, A., Rodriguez, G., Olsson, A., Jensen, L. et al. (2015). Clinical Cancer Research, vol. 21, ss. 3794-3805 DOI
Reprogramming during epithelial to mesenchymal transition under the control of TGF beta.
Tan, E., Olsson, A., Moustakas, A. (2015). CELL ADHESION & MIGRATION, vol. 9, ss. 233-246 DOI
Vaccination approach to anti-angiogenic treatment of cancer.
Wentink, M., Huijbers, E., de Gruijl, T., Verheul, H., Olsson, A. et al. (2015). Biochimica et Biophysica Acta. CR. Reviews on Cancer, vol. 1855, ss. 155-171 DOI
Pleiotrophin promotes vascular abnormalization in gliomas and correlates with poor survival in patients with astrocytomas..
Zhang, L., Kundu, S., Feenstra, T., Li, X., Jin, C. et al. (2015). Science Signaling, vol. 8 DOI
Therapeutic vaccination against fibronectin ED-A attenuates progression of metastatic breast cancer..
Femel, J., Huijbers, E., Saupe, F., Cedervall, J., Zhang, L. et al. (2014). OncoTarget, vol. 5, ss. 12418-12427
Therapeutic vaccination targeting the tumour vasculature.
Olsson, A. (2014). Biochemical Society Transactions, vol. 42, ss. 1653-1657 DOI
HRG regulates tumor progression, epithelial to mesenchymal transition and metastasis via platelet-induced signaling in the pre-tumorigenic microenvironment.
Cedervall, J., Zhang, Y., Ringvall, M., Thulin, Å., Moustakas, A. et al. (2013). Angiogenesis, vol. 16, ss. 889-902 DOI
Extracellular RNA Liberates Tumor Necrosis Factor-alpha to Promote Tumor Cell Trafficking and Progression.
Fischer, S., Gesierich, S., Griemert, B., Schaenzer, A., Acker, T. et al. (2013). Cancer Research, vol. 73, ss. 5080-5089 DOI
Inflammation induced by mmp-9 enhances tumor regression of experimental breast cancer.
Leifler, K., Svensson, S., Abrahamsson, A., Bendrik, C., Robertson, J. et al. (2013). Journal of Immunology, vol. 190, ss. 4420-4430 DOI
Prediction of Preeclampsia by Combining Serum Histidine-Rich Glycoprotein and Uterine Artery Doppler.
Bolin, M., Wikström, A., Wiberg-Itzel, E., Olsson, A., Ringvall, M. et al. (2012). American Journal of Hypertension, vol. 25, ss. 1305-1310 DOI
The non-toxic and biodegradable adjuvant Montanide ISA 720/CpG can replace Freund's in a cancer vaccine targeting ED-B-a prerequisite for clinical development.
Huijbers, E., Femel, J., Andersson, K., Björkelund, H., Hellman, L. et al. (2012). Vaccine, vol. 30, ss. 225-230 DOI
Enhanced Platelet Activation Mediates the Accelerated Angiogenic Switch in Mice Lacking Histidine-Rich Glycoprotein.
Ringvall, M., Thulin, Å., Zhang, L., Cedervall, J., Tsuchida-Straeten, N. et al. (2011). PLoS ONE, vol. 6, ss. e14526- DOI
Vaccination against the extra domain-B of fibronectin as a novel tumor therapy.
Huijbers, E., Ringvall, M., Femel, J., Kalamajski, S., Lukinius, A. et al. (2010). The FASEB Journal, vol. 24, ss. 4535-4544 DOI
Fibrinogen and histidine-rich glycoprotein in early-onset preeclampsia.
Kårehed, K., Wikström, A., Olsson, A., Larsson, A., Olovsson, M. et al. (2010). Acta Obstetricia et Gynecologica Scandinavica, vol. 89, ss. 131-139 DOI
The internally truncated LRP5 receptor presents a therapeutic target in breast cancer.
Björklund, P., Svedlund, J., Olsson, A., Åkerström, G., Westin, G. (2009). PloS one, vol. 4, ss. e4243- DOI
Histidine-rich glycoprotein can prevent development of mouse experimental glioblastoma.
Kärrlander, M., Lindberg, N., Olofsson, T., Kastemar, M., Olsson, A. et al. (2009). PLoS ONE, vol. 4, ss. e8536- DOI
Regulation of histidine-rich glycoprotein (HRG) function via plasmin-mediated proteolytic cleavage.
Poon, I., Olsson, A., Hulett, M., Parish, C. (2009). Biochemical Journal, vol. 424, ss. 27-37 DOI
Identification of potent biodegradable adjuvants that efficiently break self-tolerance: a key issue in the development of therapeutic vaccines.
Ringvall, M., Huijbers, E., Ahooghalandari, P., Alekseeva, L., Andronova, T. et al. (2009). Vaccine, vol. 28, ss. 48-52 DOI
Activated platelets provide a functional microenvironment for the antiangiogenic fragment of histidine-rich glycoprotein.
Thulin, Å., Ringvall, M., Dimberg, A., Kårehed, K., Väisänen, T. et al. (2009). Molecular Cancer Research, vol. 7, ss. 1792-1802 DOI
alphaB-crystallin promotes tumor angiogenesis by increasing vascular survival during tube morphogenesis.
Dimberg, A., Rylova, S., Dieterich, L., Olsson, A., Schiller, P. et al. (2008). Blood, vol. 111, ss. 2015-2023 DOI
Histidine-rich glycoprotein protects from systemic Candida infection.
Rydengård, V., Shannon, O., Lundqvist, K., Kacprzyk, L., Chalupka, A. et al. (2008). PLoS pathogens, vol. 4, ss. e1000116- DOI
Histidine-rich glycoprotein exerts antibacterial activity.
Rydengård, V., Olsson, A., Mörgelin, M., Schmidtchen, A. (2007). The FEBS Journal, vol. 274, ss. 377-389 DOI
Minimal active domain and mechanism of action of the angiogenesis inhibitor histidine-rich glycoprotein.
Dixelius, J., Olsson, A., Thulin, Å., Lee, C., Johansson, I. et al. (2006). Cancer Research, vol. 66, ss. 2089-97 DOI
Signal transduction in endothelial cells by the angiogenesis inhibitor histidine-rich glycoprotein targets focal adhesions.
Lee, C., Dixelius, J., Thulin, Å., Kawamura, H., Claesson-Welsh, L. et al. (2006). Experimental Cell Research, vol. 312, ss. 2547-2556 DOI
VEGF receptor signalling: in control of vascular function.
Olsson, A., Dimberg, A., Kreuger, J., Claesson-Welsh, L. (2006). Nature reviews. Molecular cell biology, vol. 7, ss. 359-371 DOI
The Anti-angiogenic His/Pro-rich Fragment of Histidine-rich Glycoprotein Binds to Endothelial Cell Heparan Sulfate in a Zn2+-dependent Manner.
Vanwildemeersch, M., Olsson, A., Gottfridsson, E., Claesson-Welsh, L., Lindahl, U. et al. (2006). Journal of Biological Chemistry, vol. 281, ss. 10298-10304 DOI
The minimal active domain of endostatin is a heparin-binding motif that mediates inhibition of tumor vascularization.
Olsson, A., Johansson, I., Åkerud, H., Einarsson, B., Christofferson, R. et al. (2004). Cancer Research, vol. 64, ss. 9012-9017 DOI
A fragment of histidine-rich glycoprotein is a potent inhibitor of tumor vascularization.
Olsson, A., Larsson, H., Dixelius, J., Johansson, I., Lee, C. et al. (2004). Cancer Research, vol. 64, ss. 599-605
Activation of Ras, Raf-1 and protein kinase C in differentiating human neuroblastoma cells after treatment with phorbolester and NGF.
Söderholm, H., Olsson, A., Lavenius, E., Rönnstrand, L., Nånberg, E. (2001). Cellular Signalling, vol. 13, ss. 95-104 DOI