Publikationer
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The endoplasmic reticulum-resident collagen chaperone Hsp47 interacts with and promotes the secretion of decorin, fibromodulin, and lumican.
(2018). Journal of Biological Chemistry, . vol. 293, ss. 13707-13716 DOI -
Integrin αVβ3 can substitute for collagen‐binding β1‐integrins in vivo to maintain a homeostatic interstitial fluid pressure.
(2018). Experimental Physiology, vol. 103, ss. 629-634 DOI -
Inhibition of integrin alpha(V)beta(6) changes fibril thickness of stromal collagen in experimental carcinomas.
(2018). Cell Communication and Signaling, . vol. 16 DOI -
Imatinib increases oxygen delivery in extracellular matrix-rich but not in matrix-poor experimental carcinoma.
(2017). Journal of Translational Medicine, . vol. 15 DOI -
Fibromodulin deficiency reduces collagen structural network but not glycosaminoglycan content in a syngeneic model of colon carcinoma..
(2017). PLOS ONE, vol. 12 DOI -
PDGF-BB enhances collagen gel contraction through a PI3K-PLCγ-PKC-cofilin pathway.
(2017). Scientific Reports, vol. 7 DOI -
Normal oral keratinocytes and head and neck squamous carcinoma cells induce an innate response in fibroblasts.
(2016). Anticancer Research, vol. 36, ss. 2131-2137 -
Fibromodulin Interacts with Collagen Cross-linking Sites and Activates Lysyl Oxidase..
(2016). Journal of Biological Chemistry, vol. 291, ss. 7951-60 DOI -
The Tyrosine Kinase Inhibitor Imatinib Augments Extracellular Fluid Exchange and Reduces Average Collagen Fibril Diameter in Experimental Carcinoma.
(2016). Molecular Cancer Therapeutics, vol. 15, ss. 2455-2464 DOI -
O-15-Water PET Study of the Effect of Imatinib, a Selective Platelet-Derived Growth Factor Receptor Inhibitor, Versus Anakinra, an IL-1R Antagonist, on Water-Perfusable Tissue Fraction in Colorectal Cancer Metastases.
(2015). Journal of Nuclear Medicine, vol. 56, ss. 1144-1149 DOI -
Increased C-telopeptide Cross-linking of Tendon Type I Collagen in Fibromodulin-deficient Mice.
(2014). Journal of Biological Chemistry, vol. 289, ss. 18873-18879 DOI -
Fibrin binds to collagen and provides a bridge for alpha V beta 3 integrin-dependent contraction of collagen gels.
(2014). Biochemical Journal, vol. 462, ss. 113-123 DOI -
Keratinocytes and Head and Neck Squamous Cell Carcinoma Cells Regulate Urokinase-type Plasminogen Activator and Plasminogen Activator Inhibitor-1 in Fibroblasts.
(2013). Anticancer Research, vol. 33, ss. 3113-3118 -
Mice Lacking NCF1 Exhibit Reduced Growth of Implanted Melanoma and Carcinoma Tumors.
(2013). PLOS ONE, vol. 8, ss. e84148- DOI -
Increased Fibrosis and Interstitial Fluid Pressure in Two Different Types of Syngeneic Murine Carcinoma Grown in Integrin β3-Subunit Deficient Mice.
(2012). PLOS ONE, vol. 7, ss. e34082- DOI -
Interleukin-1-mediated effects of normal oral keratinocytes and head and neck squamous carcinoma cells on extracellular matrix related gene expression in fibroblasts.
(2012). Oral Oncology, vol. 48, ss. 1236-1241 DOI -
Counterbalancing angiogenic regulatory factors control the rate of cancer progression and survival in a stage-specific manner.
(2011). Proceedings of the National Academy of Sciences of the United States of America, vol. 108, ss. 9939-9944 DOI -
Type I interferon system activation and association with disease manifestations in systemic sclerosis.
(2010). Annals of the Rheumatic Diseases, vol. 69, ss. 1396-1402 DOI -
Edema and fluid dynamics in connective tissue remodelling.
(2010). Journal of Molecular and Cellular Cardiology, vol. 48, ss. 518-523 DOI -
Transcapillary exchange: role and importance of the interstitial fluid pressure and the extracellular matrix.
(2010). Cardiovascular Research, vol. 87, ss. 211-217 DOI -
The streptococcal collagen-binding protein CNE specifically interferes with {alpha}V{beta}3-mediated cellular interactions with triple helical collagen.
(2010). Journal of Biological Chemistry, vol. 285, ss. 35803-35813 DOI -
Combined anti-angiogenic therapy targeting PDGF and VEGF receptors lowers the interstitial fluid pressure in a murine experimental carcinoma.
(2009). PloS one, vol. 4, ss. e8149- DOI -
Integrin α1β1 is Involved in the Differentiation into Myofibroblasts in Adult Reactive Tissues in vivo.
(2009). Journal of Cellular and Molecular Medicine (Print), vol. 13, ss. 3449-3462 DOI -
Lowered albumin extravasation rate in heart but not in other organs in beta3-integrin-deficient mice.
(2009). Acta Physiologica, vol. 197, ss. 305-311 DOI -
Opposite effects of PDGF-BB and prostaglandin E(1) on cell-motility related processes are paralleled by modifications of distinct actin-binding proteins.
(2009). Experimental Cell Research, vol. 315, ss. 1745-1758 DOI -
A secreted collagen- and fibronectin-binding streptococcal protein modulates cell-mediated collagen gel contraction and interstitial fluid pressure.
(2008). Journal of Biological Chemistry, vol. 283, ss. 1234-1242 DOI -
Peritumoral TNF alpha administration influences tumour stroma structure and physiology independently of growth in DMBA-induced mammary tumours.
(2008). Scandinavian Journal of Clinical and Laboratory Investigation, vol. 68, ss. 602-611 DOI -
Integrin alphavbeta3 acts downstream of insulin in normalization of interstitial fluid pressure in sepsis and in cell-mediated collagen gel contraction.
(2008). American Journal of Physiology. Heart and Circulatory Physiology, vol. 295, ss. H555-60 DOI -
Immuno-PET of undifferentiated thyroid carcinoma with radioiodine-labelled antibody cMAb U36: application to antibody tumour uptake studies.
(2007). European Journal of Nuclear Medicine and Molecular Imaging, vol. 34, ss. 1376-1387 DOI -
Collagen-binding proteoglycan fibromodulin can determine stroma matrix structure and fluid balance in experimental carcinoma.
(2007). Proceedings of the National Academy of Sciences of the United States of America, vol. 104, ss. 13966-13971 DOI -
Control of Interstitial Fluid Homeostasis: Roles of Growth Factors and Integrins.
(2007). I Vascular Complications in Human Diseae, . ss. 106-115 -
Dämpad inflammation gör kemoterapi effektivare.
(2007). Onkologi i Sverige, ss. 34-41 -
An interstitial network of podoplanin-expressing cells in the human endolymphatic duct.
(2006). Journal of the Association for Research in Otolaryngology, vol. 7, ss. 38-47 DOI -
Platelet-derived growth factor BB-mediated normalization of dermal interstitial fluid pressure after mast cell degranulation depends on beta3 but not beta1 integrins.
(2006). Circulation Research, vol. 98, ss. 635-641 DOI -
A fibronectin-binding protein from Streptococcus equi binds collagen and modulates cell-mediated collagen gel contraction.
(2006). Biochemical and Biophysical Research Communications, vol. 340, ss. 604-610 -
A fibronectin-binding protein from Streptococcus equi binds collagen and modulates cell-mediated collagen gel contraction.
(2006). Biochemical and Biophysical Research Communications - BBRC, vol. 340, ss. 604-610 DOI -
2-methoxyestradiol induces apoptosis in cultured human anaplastic thyroid carcinoma cells.
(2006). Thyroid, vol. 16, ss. 143-50 -
Knockout mouse models have provided invaluable insights into vascular development.
(2006). I Encyclopedia of the Microvasculature, . ss. 1109-1114 -
Inhibition of carcinoma cell-derived VEGF reduces inflammatory characteristics in xenograft carcinoma.
(2006). International Journal of Cancer, vol. 119, ss. 2795-2802 DOI -
High-dose, short-term, anti-inflammatory treatment with dexamethasone reduces growth and augments the effects of 5-fluorouracil on dimethyl-alpha- benzanthracene-induced mammary tumors in rats.
(2006). Scandinavian Journal of Clinical and Laboratory Investigation, vol. 66, ss. 477-486 DOI -
Inhibition of TGF-beta modulates macrophages and vessel maturation in parallel to a lowering of interstitial fluid pressure in experimental carcinoma.
(2005). Laboratory Investigation, vol. 85, ss. 512-521 DOI -
Platelet-derived growth factor-BB modulates membrane mobility of beta1 integrins..
(2004). Biochem Biophys Res Commun, vol. 314, ss. 89-96 -
High interstitial fluid pressure - an obstacle in cancer therapy..
(2004). Nat Rev Cancer, vol. 4, ss. 806-13 -
Analysis of gene expression in fibroblasts in response to keratinocyte-derived factors in vitro:potential implications for the wound healing process.
(2004). Journal of Investigative Dermatology, vol. 122, ss. 216-21 -
Network organization of interstitial connective tissue cells in the human endolymphatic duct.
(2003). Journal of Histochemistry and Cytochemistry, vol. 51, ss. 1491-1500 -
Network organization of interstitial connective tissue cells in the human endolymphatic duct.
(2003). Journal of Histochemistry and Cytochemistry, vol. 51, ss. 1491-500 DOI -
Hyaluronan content in experimental carcinoma is not correlated to interstitial fluid pressure..
(2003). Biochem. Biophys. Res. Commun., vol. 305, ss. 1017-1023 -
PDGF receptors as cancer drug targets..
(2003). Cancer Cell, vol. 3, ss. 439- -
STI571 enhances the therapeutic index of epothilone B by a tumor-selectiveincrease of drug uptake..
(2003). Clin Cancer Res, vol. 9, ss. 3779- -
Expression of hyaluronan synthase 2 or hyaluronidase 1 differentially affect the growth rate of transplantable colon carcinoma cell tumors..
(2002). Int J Cancer, vol. 102, ss. 212- -
Interference with TGF-β1 and -β3 in Tumor Stroma Lowers Tumor Interstitial Fluid Pressure Independently of Growth in Experimental Carcinoma.
(2002). International Journal of Cancer, vol. 102, ss. 453-462 -
Keratinocytes inhibit expression of connective tissue growth factor in fibroblasts in vitro by an interleukin-1alpha dependent mecanism.
(2002). Journal of Investigative Dermatology, vol. 119, ss. 449-455 DOI -
Inhibition of PDGF receptor signaling in tumor stroma enhances antitumor effect of chemotherapy.
(2002). Cancer Research, vol. 62, ss. 5476-5484 -
Inhibition of platelet-derived growth factor receptors reduces interstitial hypertension and increases transcapillary transport in tumors..
(2001). Cancer Res, vol. 61, ss. 2929- -
Inhibition of platelet-derived growth factor receptors reduces interstitial hypertension and increases transcapillary transport in tumors..
(2001). Cancer Research, . vol. 61, ss. 2929-2934 -
Platelet-derived growth factor beta receptor regulates interstitial fluid homeostasis through phosphatidylinositol-3' kinase signaling.
(1999). Proc Natl Acad Sci U S A, vol. 96, ss. 11410-5 -
Effects of PGE1, PGI2 and PGF2a analogs on collagen gel compaction in vitro and interstitial fluid pressure in vivo.
(1998). American Journal of Physiology, vol. 274, ss. H663-H671 -
Tumor cell and connective tissue cell interactions in human colorectal adenocarcinoma: Transfer of platelet-derived growth factor-AB/BB to stromal cells.
(1997). American Journal of Pathology, vol. 151, ss. 479-492 -
Colon-cancer cell variants producing regressive tumors in syngeneic rats, unlike variants yielding progressive tumors, attach to interstitial collagens through integrin alpha2beta1.
(1996). Int J Cancer, vol. 65, ss. 796-804 -
Stimulation of beta1 integrins on fibroblasts induces PDGF independent tyrosine phosphorylation of PDGF beta-receptors.
(1996). Journal of Cell Biology, vol. 132, ss. 741-752 -
Vitronectin in colorectal adenocarcinoma-: synthesis by stromal cells in culture.
(1994). Experimental Cell Research, vol. 214, ss. 303-312 DOI -
Tissue localization of beta receptors for platelet-derived growth factor and platelet-derived growth factor B chain during wound repair in humans.
(1993). Journal of Clinical Investigation, vol. 91, ss. 2065-2075 DOI -
Microvascular pericytes express platelet-derived growth factor-beta receptors in human healing wounds and colorectal adenocarcinoma.
(1993). American Journal of Pathology, vol. 143, ss. 1377-1388 -
Beta 1 integrin-mediated collagen gel contraction is stimulated by PDGF.
(1990). Experimental Cell Research, vol. 186, ss. 264-272 DOI