Publikationer

The protein kinase LKB1 promotes self-renewal and blocks invasiveness in glioblastoma.
Caja, L., Dadras, M., Mezheyeuski, A., Mendes Rodrigues-Junior, D., Liu, S. et al. (2022). Journal of Cellular Physiology, . vol. 237, ss. 743-762 DOI
Mast cell chymase has a negative impact on human osteoblasts.
Lind, T., Melo, F., Gustafson, A., Sundqvist, A., Zhao, X. et al. (2022). Matrix Biology, . vol. 112, ss. 1-19 DOI
TGF beta selects for pro-stemness over pro-invasive phenotypes during cancer cell epithelial-mesenchymal transition.
Tsubakihara, Y., Ohata, Y., Okita, Y., Younis, S., Eriksson, J. et al. (2022). Molecular Oncology, . vol. 16, ss. 2330-2354 DOI
The polarity protein Par3 coordinates positively self-renewal and negatively invasiveness in glioblastoma.
Dadras, M., Caja, L., Mezheyeuski, A., Liu, S., Gelabert, C. et al. (2021). Cell Death and Disease, . vol. 12 DOI
BMP2-induction of FN14 promotes protumorigenic signaling in gynecologic cancer cells.
Fukuda, T., Fukuda, R., Koinuma, D., Moustakas, A., Miyazono, K. et al. (2021). Cellular Signalling, . vol. 87 DOI
The noncoding MIR100HG RNA enhances the autocrine function of transforming growth factor beta signaling.
Papoutsoglou, P., Rodrigues Junior, D., Morén, A., Bergman, A., Pontén, F. et al. (2021). Oncogene, . vol. 40, ss. 3748-3765 DOI
BMP signaling is a therapeutic target in ovarian cancer.
Fukuda, T., Fukuda, R., Tanabe, R., Koinuma, D., Koyama, H. et al. (2020). Cell Death Discovery, vol. 6 DOI
TGF beta and EGF signaling orchestrates the AP-1-and p63 transcriptional regulation of breast cancer invasiveness.
Sundqvist, A., Vasilaki, E., Voytyuk, O., Bai, Y., Morikawa, M. et al. (2020). Oncogene, . vol. 39, ss. 4436-4449 DOI
Upregulated BMP-Smad signaling activity in the glucuronyl C5-epimerase knock out MEF cells.
Batool, T., Fang, J., Jansson, V., Zhao, H., Gallant, C. et al. (2019). Cellular Signalling, . vol. 54, ss. 122-129 DOI
Has2 natural antisense RNA and Hmga2 promote Has2 expression during TGFβ-induced EMT in breast cancer.
Kolliopoulos, C., Lin, C., Heldin, C., Moustakas, A., Heldin, P. (2019). Matrix Biology, vol. 80, ss. 29-45 DOI
Transforming growth factor β (TGFβ) induces NUAK kinase expression to fine-tune its signaling output.
Kolliopoulos, C., Raja, E., Razmara, M., Heldin, P., Heldin, C. et al. (2019). Journal of Biological Chemistry, vol. 294, ss. 4119-4136 DOI
LXR alpha limits TGF beta-dependent hepatocellular carcinoma associated fibroblast differentiation.
Morén, A., Bellomo, C., Tsubakihara, Y., Kardassis, D., Mikulits, W. et al. (2019). Oncogenesis, vol. 8 DOI
The TGFB2-AS1 lncRNA Regulates TGF-beta Signaling by Modulating Corepressor Activity.
Papoutsoglou, P., Tsubakihara, Y., Caja, L., Morén, A., Pallis, P. et al. (2019). Cell reports, . vol. 28, ss. 3182-3198.E11 DOI
JNK-Dependent cJun Phosphorylation Mitigates TGF beta- and EGF-Induced Pre-Malignant Breast Cancer Cell Invasion by Suppressing AP-1-Mediated Transcriptional Responses.
Sundqvist, A., Voytyuk, O., Hamdi, M., Popeijus, H., Bijlsma-van der Burgt, C. et al. (2019). CELLS, . vol. 8 DOI
TANK-binding kinase 1 is a mediator of platelet-induced EMT in mammary carcinoma cells.
Zhang, Y., Valsala Madhavan Unnithan, R., Hamidi, A., Caja, L., Saupe, F. et al. (2019). The FASEB Journal, vol. 33, ss. 7822-7832 DOI
Snail mediates crosstalk between TGFβ and LXRα in hepatocellular carcinoma.
Bellomo, C., Caja, L., Fabregat, I., Mikulits, W., Kardassis, D. et al. (2018). Cell Death and Differentiation, vol. 25, ss. 885-903 DOI
Serglycin promotes breast cancer cell aggressiveness: Induction of epithelial to mesenchymal transition, proteolytic activity and IL-8 signaling.
Bouris, P., Manou, D., Sopaki-Valalaki, A., Kolokotroni, A., Moustakas, A. et al. (2018). Matrix Biology, . vol. 74, ss. 35-51 DOI
Snail regulates BMP and TGF beta pathways to control the differentiation status of glioma-initiating cells.
Caja, L., Tzavlaki, K., Dadras, M., Tan, E., Hatem, G. et al. (2018). Oncogene, vol. 37, ss. 2515-2531 DOI
Systemic and specific effects of antihypertensive and lipid-lowering medication on plasma protein biomarkers for cardiovascular diseases.
Enroth, S., Maturi, V., Berggrund, M., Bosdotter Enroth, S., Moustakas, A. et al. (2018). Scientific Reports, vol. 8 DOI
TGF-beta Family Signaling in Epithelial Differentiation and Epithelial-Mesenchymal Transition.
Kahata, K., Dadras, M., Moustakas, A. (2018). Cold Spring Harbor Perspectives in Biology, . vol. 10 DOI
TGF-beta Family Signaling in Ductal Differentiation and Branching Morphogenesis.
Kahata, K., Maturi, V., Moustakas, A. (2018). Cold Spring Harbor Perspectives in Biology, . vol. 10 DOI
Genome-wide binding of transcription factor ZEB1 in triple-negative breast cancer cells.
Maturi, V., Enroth, S., Heldin, C., Moustakas, A. (2018). Journal of Cellular Physiology, vol. 233, ss. 7113-7127 DOI
Genomewide binding of transcription factor Snail1 in triple-negative breast cancer cells.
Maturi, V., Morén, A., Enroth, S., Heldin, C., Moustakas, A. (2018). Molecular Oncology, . vol. 12, ss. 1153-1174 DOI
The TGFB2-AS1 lncRNA regulates TGFβ signaling by modulating corepressor activity.
Papoutsoglou, P., Tsubakihara, Y., Caja, L., Pallis, P., Ameur, A. et al. (2018).
The protein kinase SIK downregulates the polarity protein Par3.
Vanlandewijck, M., Dadras, M., Lomnytska, M., Mahzabin, T., Lee Miller, M. et al. (2018). OncoTarget, vol. 9, ss. 5716-5735 DOI
Overexpression of heparanase attenuated TGF-beta-stimulated signaling in tumor cells.
Batool, T., Fang, J., Barash, U., Moustakas, A., Vlodavsky, I. et al. (2017). International journal of experimental pathology (Print), vol. 98, ss. A10-A11
Overexpression of heparanase attenuated TGF-beta-stimulated signaling in tumor cells.
Batool, T., Fang, J., Barash, U., Moustakas, A., Vlodavsky, I. et al. (2017). FEBS Open Bio, vol. 7, ss. 405-413 DOI
Mechanistic Insights into Autoinhibition of the Oncogenic Chromatin Remodeler ALC1.
Lehmann, L., Hewitt, G., Aibara, S., Leitner, A., Marklund, E. et al. (2017). Molecular Cell, vol. 68, ss. 847-859.e7 DOI
Somatic Ephrin Receptor Mutations Are Associated with Metastasis in Primary Colorectal Cancer.
Mathot, L., Kundu, S., Ljungström, V., Svedlund, J., Moens, L. et al. (2017). Cancer Research, vol. 77, ss. 1730-1740 DOI
Epithelial-mesenchymal transition in cancer.
Moustakas, A., Garcia de Herreros, A. (2017). Molecular Oncology, . vol. 11, ss. 715-717 DOI
TGF beta and the nuclear receptor LXR alpha crosstalk on lipid metabolism and epithelial to mesenchymal transition in hepatocellular carcinoma.
Bellomo, C., Gahman, T., Shiau, A., Heldin, C., Moustakas, A. (2016). European Journal of Clinical Investigation, vol. 46, ss. 36-36
Single Chain Antibodies as Tools to Study transforming growth factor--Regulated SMAD Proteins in Proximity Ligation-Based Pharmacological Screens.
Blokzijl, A., Zieba, A., Hust, M., Schirrmann, T., Helmsing, S. et al. (2016). Molecular & Cellular Proteomics, vol. 15, ss. 1848-1856 DOI
Commercially Available Preparations of Recombinant Wnt3a Contain Non-Wnt Related Activities Which May Activate TGF- Signaling.
Carthy, J., Engstrom, U., Heldin, C., Moustakas, A. (2016). Journal of Cellular Biochemistry, vol. 117, ss. 938-945 DOI
Chemical regulators of epithelial plasticity reveal a nuclear receptor pathway controlling myofibroblast differentiation.
Carthy, J., Stoeter, M., Bellomo, C., Vanlandewijck, M., Heldin, A. et al. (2016). Scientific Reports, vol. 6 DOI
Signaling Receptors for TGF-beta Family Members.
Heldin, C., Moustakas, A. (2016). Cold Spring Harbor Perspectives in Biology, vol. 8 DOI
In vitro and ex vivo vanadium antitumor activity in (TGF-beta)-induced EMT. Synergistic activity with carboplatin and correlation with tumor metastasis in cancer patients.
Petanidis, S., Kioseoglou, E., Domvri, K., Zarogoulidis, P., Carthy, J. et al. (2016). International Journal of Biochemistry and Cell Biology, vol. 74, ss. 121-134 DOI
The protein kinase LKB1 negatively regulates bone morphogenetic protein receptor signaling.
Raja, E., Tzavlaki, K., Vuilleumier, R., Edlund, K., Kahata, K. et al. (2016). OncoTarget, vol. 7, ss. 1120-1143 DOI
Analysis of Epithelial-Mesenchymal Transition Induced by Transforming Growth Factor β.
Valcourt, U., Carthy, J., Okita, Y., Alcaraz, L., Kato, M. et al. (2016). I Feng, XH ; Xu, P ; Lin, X (red.) TGF-Beta Signaling, . ss. 147-181 DOI
Ras and TGF-beta signaling enhance cancer progression by promoting the Delta Np63 transcriptional program.
Vasilaki, E., Morikawa, M., Koinuma, D., Mizutani, A., Hirano, Y. et al. (2016). Science Signaling, vol. 9 DOI
Regulation of Bone Morphogenetic Protein Signaling by ADP-ribosylation.
Watanabe, Y., Papoutsoglou, P., Maturi, V., Tsubakihara, Y., Hottiger, M. et al. (2016). Journal of Biological Chemistry, vol. 291, ss. 12706-12723 DOI
Estrogen receptor alpha mediates epithelial to mesenchymal transition, expression of specific matrix effectors and functional properties of breast cancer cells.
Bouris, P., Skandalis, S., Piperigkou, Z., Afratis, N., Karamanou, K. et al. (2015). Matrix Biology, vol. 43, ss. 42-60 DOI
Tamoxifen Inhibits TGF-beta-Mediated Activation of Myofibroblasts by Blocking Non-Smad Signaling Through ERK1/2.
Carthy, J., Sundqvist, A., Heldin, A., Van Dam, H., Kletsas, D. et al. (2015). Journal of Cellular Physiology, vol. 230, ss. 3084-3092 DOI
MEG3 long noncoding RNA regulates the TGF-β pathway genes through formation of RNA-DNA triplex structures.
Mondal, T., Subhash, S., Vaid, R., Enroth, S., Uday, S. et al. (2015). Nature Communications, vol. 6 DOI
Transforming growth factor beta and bone morphogenetic protein actions in cancer progression.
Moustakas, A. (2015). The FEBS Journal, vol. 282, ss. 35-35
The mitotic checkpoint protein kinase BUB1 is an engine in the TGF-beta signaling apparatus.
Moustakas, A. (2015). Science Signaling, vol. 8 DOI
Targeting Tgf-Beta I With The Transforming Growth Factor Receptor Type I Kinase Inhibitor, Ly2157299, Modulates Stemness-Related Biomarkers In Hepatocellular Carcinoma.
Rani, B., Dituri, F., Cao, Y., Engstrom, U., Lupo, L. et al. (2015). Journal of Hepatology, vol. 62, ss. S429-S429
The high mobility group A2 protein epigenetically silences the Cdh1 gene during epithelial-to-mesenchymal transition.
Tan, E., Kahata, K., Idås, O., Thuault, S., Heldin, C. et al. (2015). Nucleic Acids Research, vol. 43, ss. 162-178 DOI
Fine-Tuning of Smad Protein Function by Poly(ADP-Ribose) Polymerases and Poly(ADP-Ribose) Glycohydrolase during Transforming Growth Factor β Signaling.
Dahl, M., Maturi, V., Lönn, P., Papoutsoglou, P., Zieba, A. et al. (2014). PLOS ONE, vol. 9, ss. e103651- DOI
Nucleosome regulatory dynamics in response to TGF-beta treatment in HepG2 cells.
Enroth, S., Andersson, R., Bysani, M., Wallerman, O., Tuch, B. et al. (2014). Nucleic Acids Research, vol. 42, ss. 6921-6934 DOI
Nucleosome regulatory dynamics in response to TGF beta.
Enroth, S., Andersson, R., Bysani, M., Wallerman, O., Termén, S. et al. (2014). Nucleic Acids Research, vol. 42, ss. 6921-6934 DOI
Invasive cells follow Snail's slow and persistent pace.
García de Herreros, A., Moustakas, A. (2014). Cell Cycle, vol. 13, ss. 2320-2321 DOI
Knock-Down of CD44 Regulates Endothelial Cell Differentiation via NF kappa B-Mediated Chemokine Production.
Olofsson, B., Porsch, H., Heldin, P. (2014). PLOS ONE, vol. 9, ss. e90921- DOI
HRG regulates tumor progression, epithelial to mesenchymal transition and metastasis via platelet-induced signaling in the pre-tumorigenic microenvironment.
Cedervall, J., Zhang, Y., Ringvall, M., Thulin, Å., Moustakas, A. et al. (2013). Angiogenesis, vol. 16, ss. 889-902 DOI
The Epstein-Barr virus nuclear antigen-1 reprograms transcription by mimicry of high mobility group A proteins.
Coppotelli, G., Mughal, N., Callegari, S., Sompallae, R., Caja Puigsubira, L. et al. (2013). Nucleic Acids Research, vol. 41, ss. 2950-2962 DOI
Serglycin Is Implicated in the Promotion of Aggressive Phenotype of Breast Cancer Cells.
Korpetinou, A., Skandalis, S., Moustakas, A., Happonen, K., Tveit, H. et al. (2013). PLOS ONE, vol. 8, ss. e78157- DOI
Coordination of TGF-beta Signaling by Ubiquitylation.
Moustakas, A., Heldin, C. (2013). Molecular Cell, vol. 51, ss. 555-556 DOI
TGF-beta in Human Disease.
Moustakas, Aristidis; Miyazawa, Keiji, 2013 DOI
p53 regulates epithelial-mesenchymal transition induced by transforming growth factor β.
Termén, S., Tan, E., Heldin, C., Moustakas, A. (2013). Journal of Cellular Physiology, vol. 228, ss. 801-813 DOI
Context-dependent action of transforming growth factor β family members on normal and cancer stem cells.
Caja, L., Kahata, K., Moustakas, A. (2012). Current pharmaceutical design, vol. 18, ss. 4072-4086 DOI
Transcriptional induction of salt-inducible kinase 1 by transforming growth factor β leads to negative regulation of type I receptor signaling in cooperation with the Smurf2 ubiquitin ligase.
Lönn, P., Vanlandewijck, M., Raja, E., Kowanetz, M., Watanabe, Y. et al. (2012). Journal of Biological Chemistry, vol. 287, ss. 12867-12878 DOI
Induction of epithelial-mesenchymal transition by transforming growth factor β.
Moustakas, A., Heldin, C. (2012). Seminars in Cancer Biology, vol. 22, ss. 446-454 DOI
Differential regulation of the two RhoA-specific GEF isoforms Net1/Net1A by TGF-β and miR-24: role in epithelial-to-mesenchymal transition.
Papadimitriou, E., Vasilaki, E., Vorvis, C., Iliopoulos, D., Moustakas, A. et al. (2012). Oncogene, vol. 31, ss. 2862-2875 DOI
Regulation of transcription factor Twist expression by the DNA architectural protein high mobility group A2 during epithelial-to-mesenchymal transition.
Tan, E., Thuault, S., Caja, L., Carletti, T., Heldin, C. et al. (2012). Journal of Biological Chemistry, vol. 287, ss. 7134-7145 DOI
Intercellular variation in signaling through the TGF-β pathway and its relation to cell densityand cell cycle phase.
Zieba, A., Pardali, K., Söderberg, O., Lindbom, L., Nyström, E. et al. (2012). Molecular & Cellular Proteomics, . vol. 11 DOI
Hyaluronan synthase 2 (HAS2) promotes breast cancer cell invasion by suppression of tissue metalloproteinase inhibitor 1 (TIMP-1).
Bernert, B., Porsch, H., Heldin, P. (2011). Journal of Biological Chemistry, vol. 286, ss. 42349-42359 DOI
Immortalized keratinocytes derived from patients with epidermolytic ichthyosis reproduce the disease phenotype: A useful in vitro model for testing new treatments.
Chamcheu, J., Pihl-Lundin, I., Eteti Mouyobo, C., Gester, T., Virtanen, M. et al. (2011). British Journal of Dermatology, . vol. 164, ss. 263-272 DOI
Regulation of Myosin Light Chain Function by BMP Signaling Controls Actin Cytoskeleton Remodeling.
Konstantinidis, G., Moustakas, A., Stournaras, C. (2011). Cellular Physiology and Biochemistry, vol. 28, ss. 1031-1044 DOI
Negative regulation of TGFβ signaling by the kinase LKB1 and the scaffolding protein LIP1.
Morén, A., Raja, E., Heldin, C., Moustakas, A. (2011). Journal of Biological Chemistry, vol. 286, ss. 341-353 DOI
TGFβ-induced early activation of the small GTPase RhoA is Smad2/3-independent and involves Src and the guanine nucleotide exchange factor Vav2.
Papadimitriou, E., Kardassis, D., Moustakas, A., Stournaras, C. (2011). Cellular Physiology and Biochemistry, Basel: Karger. vol. 28, ss. 229-238 DOI
Role of TGF-β signaling in EMT, cancer progression and metastasis.
Savary, K., Moustakas, A. (2011). Drug Discovery Today , . vol. 8, ss. 121-126 DOI
Cdc6 expression represses E-cadherin transcription and activates adjacent replication origins.
Sideridou, M., Zakopoulou, R., Evangelou, K., Liontos, M., Kotsinas, A. et al. (2011). Journal of Cell Biology, vol. 195, ss. 1123-1140 DOI
The notch and TGF-β signaling pathways contribute to the aggressiveness of clear cell renal cell carcinoma..
Sjölund, J., Boström, A., Lindgren, D., Manna, S., Moustakas, A. et al. (2011). PLOS ONE, vol. 6, ss. e23057- DOI
TGF beta Activates Mitogen- and Stress-activated Protein Kinase-1 (MSK1) to Attenuate Cell Death.
van der Heide, L., van Dinther, M., Moustakas, A., ten Dijke, P. (2011). Journal of Biological Chemistry, vol. 286, ss. 5003-5011 DOI
Hyaluronan Synthesis Is Inhibited by Adenosine Monophosphate-activated Protein Kinase through the Regulation of HAS2 Activity in Human Aortic Smooth Muscle Cells.
Vigetti, D., Clerici, M., Deleonibus, S., Karousou, E., Viola, M. et al. (2011). Journal of Biological Chemistry, vol. 286, ss. 7917-7924 DOI
Quantitative analysis of transient and sustained transforming growth factor-beta signaling dynamics.
Zi, Z., Feng, Z., Chapnick, D., Dahl, M., Deng, D. et al. (2011). Molecular Systems Biology, . vol. 7 DOI
Transforming growth factor β promotes complexes between Smad proteins and the CCCTC-binding factor on the H19 imprinting control region chromatin.
Bergström, R., Savary, K., Morén, A., Guibert, S., Heldin, C. et al. (2010). Journal of Biological Chemistry, USA: The American Society for Biochemistry and Molecular Biology, Inc.. vol. 285, ss. 19727-19737 DOI
Immortalized keratinocytes from Epidermolytic Ichthyosis-patients reproduce the disease phenotype in vitro.
Chamcheu, J., Virtanen, M., Moustakas, A., Navsaria, H., Vahlquist, A. et al. (2010). Journal of Investigative Dermatology, vol. 130, ss. S83-S83
The activity of hyaluronan synthase 2 is regulated by dimerization and ubiquitination.
Karousou, E., Kamiryo, M., Skandalis, S., Ruusala, A., Asteriou, T. et al. (2010). Journal of Biological Chemistry, USA: The American Society for Biochemistry and Molecular Biology, Inc.. vol. 285, ss. 23647-23654 DOI
PARP-1 attenuates Smad-mediated transcription.
Lönn, P., van der Heide, L., Dahl, M., Hellman, U., Heldin, C. et al. (2010). Molecular Cell, vol. 40, ss. 521-532 DOI
Integrins open the way to epithelial-mesenchymal transitions: Comment on: Bianchi A, et al. Cell Cycle 2010; 9:1647–59.
Moustakas, A. (2010). Cell Cycle, . vol. 9, ss. 1682-1682 DOI
Proteomic identification of CD44 interacting proteins.
Skandalis, S., Kozlova, I., Engström, U., Hellman, U., Heldin, P. (2010). IUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology, vol. 62, ss. 833-840 DOI
Characterization of immortalized human epidermolysis bullosa simplex (KRT5) cell lines: trimethylamine N-oxide protects the keratin cytoskeleton against disruptive stress condition.
Chamcheu, J., Lorié, E., Akgul, B., Bannbers, E., Virtanen, M. et al. (2009). Journal of dermatological science (Amsterdam), . vol. 53, ss. 198-206 DOI
Growth factor regulation of hyaluronan deposition in malignancies..
Heldin, P., Karousou, E., Skandalis, S. (2009). I Robert Stern (red.) Hyaluronan in Cancer Biology., San Diego, Calif.: Elsevier Inc.. ss. 37-50 DOI
Emergence, development and diversification of the TGF-beta signalling pathway within the animal kingdom.
Huminiecki, L., Goldovsky, L., Freilich, S., Moustakas, A., Ouzounis, C. et al. (2009). BMC Evolutionary Biology, . vol. 9, ss. 28- DOI
Epithelial-mesenchymal transition as a mechanism of metastasis.
Savary, K., Termén, S., Thuault, S., Keshamouni, V., Moustakas, A. (2009). I Keshamouni, V., Arenberg, D., Kalemkerian, G. (red.) Lung Cancer Metastasis, . ss. 65-92 DOI
A SNAIL1–SMAD3/4 transcriptional repressor complex promotes TGF‑β mediated epithelial–mesenchymal transition.
Vincent, T., Neve, E., Johnson, J., Kukalev, A., Rojo, F. et al. (2009). Nature Cell Biology, vol. 11, ss. 943-950 DOI
Sustained TGF beta exposure suppresses Smad and non-Smad signalling in mammary epithelial cells, leading to EMT and inhibition of growth arrest and apoptosis.
Gal, A., Sjöblom, T., Fedorova, L., Imreh, S., Beug, H. et al. (2008). Oncogene, vol. 27, ss. 1218-1230 DOI
Importance of hyaluronan-CD44 interactions in inflammation and tumorigenesis.
Heldin, P., Karousou, E., Bernert, B., Porsch, H., Nishitsuka, K. et al. (2008). Connective Tissue Research, vol. 49, ss. 215-218 DOI
TGFβ induces SIK to negatively regulate type I receptor kinase signaling.
Kowanetz, M., Lönn, P., Vanlandewijck, M., Kowanetz, K., Heldin, C. et al. (2008). Journal of Cell Biology, . vol. 182, ss. 655-662 DOI
Cancer-associated fibroblasts and the role of TGFbeta.
Micke, P., Moustakas, A., Ohshima, M., Kappert, K. (2008). I Jakowlew, Sonia B. (red.) Transforming Growth Factor-beta in Cancer Therapy, Vol II, Totowa, NJ: The Humana Press, Inc.. ss. 417-441 DOI
TGF-beta Targets PAX3 to Control Melanocyte Differentiation.
Moustakas, A. (2008). Developmental Cell, vol. 15, ss. 797-799 DOI
HMGA2 and Smads co-regulate SNAIL1 expression during induction of epithelial-to-mesenchymal transition.
Thuault, S., Tan, E., Peinado, H., Cano, A., Heldin, C. et al. (2008). Journal of Biological Chemistry, vol. 283, ss. 33437-33446 DOI
TGF-beta and Smad signaling in transcriptome reprogramming during EMT.
Thuault, S., Valcourt, U., Kowanetz, M., Moustakas, A. (2008). I Sonia B. Jakowlew (red.) Transforming Growth Factor-Beta in Cancer Therapy Totowa, NJ: The Human Press Inc..
Growth factor regulation of hyaluronan synthesis and degradation in human dermal fibroblasts: importance of hyaluronan for the mitogenic response of PDGF-BB.
Li, L., Asteriou, T., Bernert, B., Heldin, C., Heldin, P. (2007). Biochemical Journal, vol. 404, ss. 327-336 DOI
Silencing of hyaluronan synthase 2 suppresses the malignant phenotype of invasive breast cancer cells.
Li, Y., Li, L., Brown, T., Heldin, P. (2007). International Journal of Cancer, vol. 120, ss. 2557-2567 DOI
Notch signaling is necessary for epithelial growth arrest by TGF-beta.
Niimi, H., Pardali, K., Vanlandewijck, M., Heldin, C., Moustakas, A. (2007). Journal of Cell Biology, vol. 176, ss. 695-707 DOI
Functional role of Meox2 during the epithelial cytostatic response to TGF-beta.
Valcourt, U., Thuault, S., Pardali, K., Heldin, C., Moustakas, A. (2007). Molecular Oncology, vol. 1, ss. 55-71 DOI
Operational criteria for selecting a cDNA microarray data normalization algorithm.
Argyropoulos, C., Chatziioannou, A., Nikiforidis, G., Moustakas, A., Kollias, G. et al. (2006). Oncology Reports, vol. 15, ss. 983-996
A new twist in Smad signaling.
Heldin, C., Moustakas, A. (2006). Developmental Cell, vol. 10, ss. 685-686 DOI
The mechanism of nuclear export of smad3 involves exportin 4 and Ran.
Kurisaki, A., Kurisaki, K., Kowanetz, M., Sugino, H., Yoneda, Y. et al. (2006). Molecular and Cellular Biology, vol. 26, ss. 1318-1332 DOI

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