Dissertations at IMBIM
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C8:301, BMC, Husargatan 3, Uppsala 2021-10-19 10:00
Kolliopoulos, Constantinos
Role of TGFβ-induced hyaluronan-CD44 signaling in cancer progression
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Tzavlaki, Kalliopi
Regulation of cell differentiation and invasion by members of the TGFß family
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Naboulsi, Rakan
Animal genomics – gene discovery and gene characterization
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Abdalaal, Hind
Deciphering molecular mechanisms in the evolution of new functions
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Han, Fan
Genetic Adaptation and Speciation in Darwin’s Finches and Atlantic Herring
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Paivandy, Aida
Induction of Mast Cell Apoptosis via Granule Permeabilization: A Novel Approach to Target Mast Cells
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Sakthikumar, Sharadha
Characterizing the spectrum of somatic alterations in canine and human cancers
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Eriksson, Per
Avian Influenza Virus: Deciphering receptor interactions and their role in interspecies transmission
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Nordin, Jessika
Human leukocyte antigen in sickness and in health: Ankylosing spondylitis and HLA in Sweden
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Rajer, Fredrika
Multi-Resistance Plasmids: Fitness Costs, Dynamics and Evolution
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Mathioudaki, Argyri
Complex disease genetics: Utilising targeted sequencing and homogeneous ancestry
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Mun, Kwangchol
Human adenovirus – host cell interplay: The role of the cellular zinc finger proteins and mitochondrial DNA
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Salomonsson, Maya
New Aspects of Mast Cell Progenitors in Health and Disease
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Tsioumpekou, Maria
Studies of PDGF receptor signaling in vitro and in vivo
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Saez-Ibañez, Ana Rosa
Novel roles of ErbB3 receptor tyrosine kinase in vesicular trafficking
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Song, Tianyi
Understanding Heparan Sulfate Biosynthesis and Functional Implications of Heparanase
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Batool, Tahira
Heparan sulfate dependent cell signaling and associated pathophysiology: Implications in tumorigenesis and embryogenesis
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Albrecht, Lisa M.
Antibiotic Resistance: Selection in the Presence of Metals and Antimicrobials
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Megquier, Kate
Analysis of inherited and somatic variants to decipher canine complex traits
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Åberg, Emma
Evolution of Interactions Involving Intrinsically Disordered Proteins
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Shahidi Dadras, Mahsa
Regulation of cell polarity and invasion by TGF-β and BMP signaling
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Garmendia, Eva
A Unified Multitude: Experimental Studies of Bacterial Chromosome Organization
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Thulin, Elisabeth
Mechanisms and Dynamics of Mecillinam Resistance in Escherichia coli
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Singh, Kailash
Regulatory T cells in type 1 diabetes: the role of IL-35 in counteracting the disease
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Younis, Shady
Functional characterization of the biological significance of the ZBED6/ZC3H11A locus in placental mammals
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Inturi, Raviteja
Functional characterization of the human adenovirus pVII protein and non-coding VA RNAI
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Praski Alzrigat, Lisa
Constraints on up-regulation of drug efflux in the evolution of ciprofloxacin resistance
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Bianchi, Matteo
Genetic Studies of Immunological Diseases in Dogs and Humans
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Bergström, Joakim
A Search for the Masked Mechanism Behind IgG-Mediated Suppression of Antibody Responses
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Zhang, Lu
IgG3 Complements IgM in the Complement-Mediated Regulation of Immune Responses
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Digre, Andreas
Implications of Heparan Sulfate and Heparanase in Inflammatory Diseases
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Rafati, Nima
Exploring genetic diversity in natural and domestic populations through next generation sequencing
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Karlsson, Andreas
Characterization and Engineering of Protein-Protein Interactions Involving PDZ Domains
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Zhang, Yanyu
Platelets – Multifaceted players in tumor progression and vascular function
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Zarnegar, Behdad
Mechanisms triggering the recruitment of mast cell progenitors to the lung and regulation of mast cell degranulation
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Xu, Hui
Modulation of B cell access to antigen by passively administered antibodies: an explanation for antibody feedback regulation?
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Lofton Tomenius, Hava
Mechanisms and Biological Costs of Bacterial Resistance to Antimicrobial Peptides
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Kamel, Wael
Adenoviral small non-coding RNAs: A Structural and Functional Charaterization
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Lamichhaney, Sangeet
The genetic basis for adaptation in natural populations
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Namburi, Ramesh Babu
Brittlestars Galactosaminoglycans and Tools to Study their Structure
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Tengvall, Katarina
Genetic Studies in Dogs Implicate Novel Genes Involved in Atopic Dermatitis and IgA Deficiency
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Imsland, Freyja
Monogenic Traits Associated with Structural Variants in Chicken and Horse: Allelic and Phenotypic Diversity of Visually Appealing Traits
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Linkevičius, Marius
Evolution and Mechanisms of Tigecycline Resistance in Escherichia coli
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Pijuan Galitó, Sara
Novel Culture Strategies and Signal Transduction Pathways of Pluripotent Stem Cells
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Östberg, Sara
Functional Characterization of the Evolutionarily Conserved Adenoviral Proteins L4-22K and L4-33K
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Ding, Zhoujie
Feedback Enhancement of Immune Responses by IgE, IgM, and IgG3 Antibodies
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Gullberg, Erik
Selection of Resistance at very low Antibiotic Concentrations
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Bergman, Jessica M.
Genetics and Growth Regulation in Salmonella enterica
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Berglund, Jonas
Meiotic Recombination in Human and Dog: Targets, Consequences and Implications for Genome Evolution
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Femel, Julia
Therapeutic Cancer Vaccines Targeting Molecules Associated with Tumor Angiogenesis
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Adler, Marlen
Mechanisms and Dynamics of Carbapenem Resistance in Escherichia coli
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Reyhani, Vahid
Extracellular Matrix and Actin Cytoskeleton - the Control Unit of Interstitial Fluid Volume
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Heldin, Johan
Identification and Characterization of Proteins and MicroRNAs that Modulate Receptor Signaling, Vesicular Trafficking and Cell Migration in Vascular Cells
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Ratnakumar, Abhirami
Detecting Signatures of Selection within the Dog Genome
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Dahlin, Joakim
Mast Cell Progenitor Trafficking in Allergic Airway Inflammation
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Eriksson, Anna S.
Syndecan - Regulation and Function of its Glycosaminoglycan Chains
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Fredlund Fuchs, Peder
Myofibroblasts and the Vascular Endothelium: Impact of Fibrin Degradation Products and miRNA on Vascular Motility and Function
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Riaz, Anjum
Adhesion Dependent Signals: Cell Survival, Receptor Crosstalk and Mechanostimulation
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Jiang, Lin
Functional Studies of Genes Associated with Muscle Growth in Pigs and Hair Greying in Horses
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Olsson, Mia
Uncovering a Novel Pathway for Autoinflammation: With a Little Help from a Wrinkled Friend
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Ramachandra, Rashmi
Galactosaminoglycans - Role in Brittlestar Limb Regeneration
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Roy, Ananya
Mast Cells as Sentinels: Role of serglycin and mast cell proteases in infection and inflammation
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Nordberg, Niklas
Studies of Budding Yeast Transcription Factors Acting Downstream of Nutrient Signaling Pathways
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Beckman Sundh, Ulla
Studies on Phosphohistidine Phosphatase 1: What? Where? Why?
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Huijbers, Elisabeth J. M
Development of a Cancer Vaccine Targeting Tumor Blood Vessels
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Zeller, Kathrin Stephanie
Integrin Signaling in Cell Adhesion and Mechanotransduction: Regulation of PI3K, AKT, and ROS
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Tranell, Anna
Regulation of HIV-1 mRNA Processing by Cellular Splicing Factors
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Eriksson, Jonas
Genetic and Genomic Studies in Chicken: Assigning Function to Vertebrate Genes
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Haq, Syed Raza ul
Molecular Mechanisms of Folding and Binding in PDZ Domains
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Törmänen Persson, Heidi
The Adenovirus L4-33K Protein: A Key Regulator of Virus-specific Alternative Splicing
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Kristell, Carolina
Chromatin Dynamics in the Fission Yeast, Schizosaccharomyces pombe
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Somberg, Monika
Cellular and Viral Factors that Control Human Papillomavirus Type 16 Late Gene Expression
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Tobin, Christina
Removal and Replacement of Ribosomal Proteins: Effects on Bacterial Fitness and Ribosome Function
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Kheir, Amany
Factors Influencing Evolution to Antimalarial Drug Resistance in Plasmodium falciparum in Sudan and The Gambia
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Barkefors, Irmeli
Directing Angiogenesis: Cellular Responses to Gradients in vitro
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Hjertström, Elina
Roles of Heparan Sulfate in Amyloid-β Pathology and Hypoxia
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Friman, Tomas
Extracellular Matrix and Connective Tissue Cells of the Tumor Microenvironment
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Lind, Peter A
Evolutionary Dynamics of Mutation and Gene Transfer in Bacteria
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Karén, Jakob
The Role of Microvascular Pericytes in the Generation of Pro-fibrotic Connective Tissue Cells: Investigations in vitro and in Reactive Tissues in vivo
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Sun, Wei
A New Look into Protein C Inhibitor: Posttranslational Modifications and their Functions
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Pränting, Maria
Bacterial Resistance to Antimicrobial Peptides: Rates, Mechanisms and Fitness Effects
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Chi, Celestine
Post-synaptic Density Disc Large Zo-1 (PDZ) Domains: From Folding and Binding to Drug Targeting
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Dagälv, Anders
Role of Heparan Sulfate N-sulfation in Mouse Embryonic Development
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Rodriguez, Alejandro
Studies of Stroma Formation and Regulation in Human Pathological Conditions and in Experimental in vivo Models
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Petersson, Ludvig
The Roles of Growth Factor Interactions and Mechanical Tension in Angiogenesis
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Koskiniemi, Sanna
Dynamics of the Bacterial Genome: Rates and Mechanisms of Mutation
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Thulin, Åsa
The Role of Histidine-rich Glycoprotein in Angiogenesis and Tumor Growth
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Larsson, Jimmy
Neural Stem and Progenitor Cells: Cellular Responses to Known and Novel Factors
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Wallenquist, Ulrika
Neural Stem and Progenitor Cells as a Tool for Tissue Regeneration
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Nilsson, Anders
Studies of the Carbon and Energy Metabolism in the Moss Physcomitrella patens
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Zody, Michael C.
Investigation of Mechanics of Mutation and Selection by Comparative Sequencing
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Alfredsson Timmins, Jenny
Functional organisation of the cell nucleus in the fission yeast, Schizosaccharomyces pombe
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Jia, Juan
Structure and functions of heparan sulfate/heparin – Importance of glucuronyl C5-epimerase and heparanase
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van Wieringen, Tijs
Intra- and Extracellular Modulation of Integrin-directed Connective Tissue Cell Contraction
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Backström, Ellenor
Regulation of Adenoviral Gene Expression by the L4-33K and L4-22K Proteins
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Chumnarnsilpa, Sakesit
The Structural Basis of the Control of Actin Dynamics by the Gelsolin Superfamily Proteins
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Markljung, Ellen
QTL Analysis in the Pig: From the Identification of Quantitative Trait Loci to the Understanding of Molecular Mechanisms
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Carlsson, Pernilla
Cellular design of heparan sulfate: The NDST enzymes and their regulation
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Valsecchi, Isabel
AtZDP, a Plant 3' DNA Phosphatase, Involved in DNA Repair
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Jastrebova, Nadja
Role of Heparan Sulfate Structure in FGF-Receptor Interactions and Signaling
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Martin, Nathalie
Studies on the regulation of the Napin napA promoter by ABI3, bZIP and bHLH transcription factors
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Marknell DeWitt, Åsa
Use of Recombinant Allergens for Component-Resolved Diagnostics (CRD) in IgE-Mediated Allergy
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Lövkvist, Lena
Receptor Interactions Between Pathogenic Bacteria and Host Cells
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Johansson, Carolina
Mechanisms and DNA Specificity in Site-specific Recombination of Integron Cassettes
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Aguda, Adeleke H.
Structural Study of the WH2 Family and Filamin: Implications for Actin Cytoskeleton Regulation
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Presto, Jenny
N-Sulfation and Polymerization in Heparan Sulfate Biosynthesis
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Berg, Frida
Genetic Analysis of Fat Metabolism in Domestic Pigs and their Wild Ancestor
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Kurup, Sindhulakshmi
Design of Oligosaccharide Libraries to Characterize Heparan Sulfate – Protein Interactions
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Öhrmalm, Christina
Functional Characterization of the Cellular Protein p32: A Protein Regulating Adenovirus Transcription and Splicing Through Targeting of Phosphorylation
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Nilsson, Stina
Structural and Functional Aspects of β1 Integrin Signalling
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Holmborn, Katarina
Heparan Sulfate and Development: A Study of NDST Deficient Mice and Embryonic Stem Cells
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Vanwildemeersch, Maarten
Interaction of Heparan Sulfate with Pro- and Anti-Angiogenic Proteins
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Lidén, Åsa
Integrin αVβ3-Directed Contraction by Connective Tissue Cells: Role in Control of Interstitial Fluid Pressure and Modulation by Bacterial Proteins
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Larsson, Mårten
Megalin, an Endocytotic Receptor with Signalling Potential
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Johansson, Cecilia
Modulation of Adenovirus E1A Activities by the Cellular Corepressor CtBP
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Berenjian, Saideh
Construction of Adenovirus Vectors for Studies of Protein Function and RNA Interference
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Fitzsimmons, Carolyn
Exploring the Realm of Gene Expression Differences Between White Leghorn and Red Junglefowl Chickens
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Hultgård Ekwall, Anna-Karin
Fibroblast Contractility in vivo and in vitro: Effects of Prostaglandins and Potential Role for Inner Ear Fluid Homeostasis
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Rush, Margaret
Regulation of RNA Processing in Human Papillomavirus Type 16
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Zhao, Xiaomin
Regulation of Human Papillomavirus Type 16 mRNA Splicing and Polyadenylation
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Jönsson, Maria
Microbial Responses to Antibiotics – Stability of Resistance and Extended Potential of Targeting the Folate Synthesis
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Öberg, Daniel
The Role of Polyadenylation in Human Papillomavirus Type 16 Late Gene Expression
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Smeds, Emanuel
In Vitro Studies of the Substrate Specificities of Heparan Sulfate 2-O- and 6-O-sulfotransferases
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Roman, Elisabet
Studies on the Role of UDP-Glucose Dehydrogenase in Polysaccharide Biosynthesis
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Sakwe, Amos M.
The Role of Protein Kinase C in the Extracellular Ca2+-regulated Secretion of Parathyroid Hormone
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Park, Hee-Bok
Genetic Analysis of Quantitative Traits Using Domestic Animals: A Candidate Gene and Genome Scanning Approach
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Ringvall, Maria
Functions of Heparan Sulfate During Mouse Development: Studies of Mice with Genetically Altered Heparan Sulfate Biosynthesis
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Westling, Camilla
N-Unsubstituted Glucosamine Residues in Heparan Sulfate and Their Potential Relation to Alzheimer's Disease
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Punga, Tanel
The Interaction of the Adenovirus E1B-55K Protein with a Histone Deacetylase Complex: Its Importance in Regulation of P53 Protein Functions
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Qvarnström, Yvonne
Sulphonamide Resistance in Neisseria meningitidis and Commensal Neisseria Species
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Lindberg, Anette
Viruses as a Model System for Studies of Eukaryotic mRNA Processing
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Grundström, Gunilla
Functional Studies of Collagen-Binding Integrins α2β1 and α11β1: Interplay between Integrins and Platelet-Derived Growth Factor Receptors
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Dauksaite, Vita
The Modular Domain Structure of ASF/SF2: Significance for its Function as a Regulator of RNA Splicing
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Kaczmarczyk, Aneta
Proteins of the Inter-α-inhibitor Family: Biosynthesis, Plasma Clearance and Interaction with Extracellular Matrix Components
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Zhang, Shouting
Studies on the Molecular Biology of the Mouse Pneumotropic Polyomavirus
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Wiklund, Lisa
Role of the 3'UTR in translation and stability of HCV and HPV mRNAs
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Jacobson, Annica
Regulation of hyaluronan biosynthesis: Expression in vitro and importance for tumor progression
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Ekholm Pettersson, Frida
T-cell Differentiation and Immunological Homeostasis in Lymphopenic and Kappa Light Chain Deficient Mice
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Lammerts, Ellen
Tumor Stroma in Anaplastic Thyroid Carcinoma: Interstitial Collagen and Tumor Interstitial Fluid Pressure
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Sundqvist, Anders
Characterisation of CtBP: A Co-Repressor of Transcription that Interacts with the Adenovirus E1A Protein
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Loog, Mart
Studies on the Differential Specificity of Protein Kinases and Its Applications
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Rahmanian, Mehdi
Extracellular matrix as a regulator of cell behavior: Biological effects of hyaluronan biosynthesis and catabolism
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Molin, Magnus
Adenovirus vector systems permitting regulated protein expression and their use for in vivo splicing studies
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Houshmand, Hamid
Protein interactions involved in viral replication characterized by T7 phage display
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Brinck, Jonas
The expression and regulation of hyaluronan synthases and their role in glycosaminoglycan synthesis
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Yue, Bai-Gong
Regulation of adenovirus alternative pre-mRNA splicing: Functional characterization of exonic and intronic splicing enhancer elements
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Lohikangas, Lars
The role of 1-intergrins in skeletal muscle differentiation and extracellular matrix assembly
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Poorafshar, Maryam
Chymotrypsin/trypsin-related serine proteases: A structural, functional and evolutionary analysis
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Rong, Jianhui
Novel chemical and enzymatic routes to the generation of heparin- related polysaccarides
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Svineng, Gunbjørg
Characterisation of integrin splice variants and the interaction between integrins and the urokinase receptor
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Balciunas, Darius
Functional studies in yeast of cyclin C and the RNA polymerase II Mediator complex
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Sokolowski, Marcus
Control of human papillomavirus type 1 late mRNA stability and translation by an AU-rich RNA element
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Onyango, Isaac G.
Intracellular components involved in parathyroid sensing of extracellular calcium
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Sandbäck Pikas, Dagmar
Enzymes involved in biosynthesis and degradation of heparin-related polysaccharides
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Lind, Thomas
Enzymes involved in heparan sulfate chain elongation: Function of a novel family of tumor suppressors?
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McCourt, Peter A. G.
Hyaluronan receptors of liver endothelial cells, their purification and characterisation
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Söderbärg, Karin
Effects of polyomavirus T antigens on cellular signal transduction pathways
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Åhlén, Karina
Collagen-binding integrin α2β1 activity in vivo and in vitro: Effects of platelet-derived growth factor-BB
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Ström, Anne-Christine
Transcriptional activation by Sp1 and the adenovirus E1A transactivator protein
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Studies of Intracellular Transport and Anticancer Drug Action by Functional Genomics in Yeast
Gustavsson, Marie